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anti-BRWD1 antibody :: Chicken anti-Human WDR9 Polyclonal Antibody

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Catalog # MBS613929
Unit / Price
  0.5 mg  /  $570 +1 FREE 8GB USB
anti-BRWD1 antibody
Product Name

WDR9 (BRWD1), Polyclonal Antibody

Also Known As

WDR9 (WDR9, WD repeat domain 9, 90/3H1, FLJ11315, cAMP response element binding and beta-tranducin family-like)

Product Synonym Names
Anti -WDR9 (WDR9, WD repeat domain 9, 90/3H1, FLJ11315, cAMP response element binding and beta-tranducin family-like)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
chromosome: 21; Location: 21q22.2
3D Structure
ModBase 3D Structure for Q9NSI6
Clonality
Polyclonal
Isotype
IgY
Host
Chicken
Species Reactivity
Human
Specificity
Recognizes WDR9.3.
Purity/Purification
Purified
Purified
Form/Format
Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide.
Immunogen
Purified WDR9.3 recombinant protein
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20 degree C or colder. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-BRWD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-BRWD1 antibody
WDR9.3, a novel protein (57KD) from human chromosome 21.
Applications Tested/Suitable for anti-BRWD1 antibody
Western Blot (WB)
Application Notes for anti-BRWD1 antibody
Can be used at 1:500-1:5000 for immunoblot testing.
NCBI/Uniprot data below describe general gene information for BRWD1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
262,936 Da[Similar Products]
NCBI Official Full Name
WDR9 protein, form B
NCBI Official Synonym Full Names
bromodomain and WD repeat domain containing 1
NCBI Official Symbol
BRWD1  [Similar Products]
NCBI Official Synonym Symbols
N143; WDR9; FLJ43918; C21orf107; BRWD1
  [Similar Products]
NCBI Protein Information
bromodomain and WD repeat-containing protein 1; WD repeat domain 9; transcriptional unit N143; WD repeat protein WDR9-form2; WD repeat-containing protein 9; cAMP response element binding and beta-tranducin family-like
UniProt Protein Name
Bromodomain and WD repeat-containing protein 1
UniProt Synonym Protein Names
WD repeat-containing protein 9
UniProt Gene Name
BRWD1  [Similar Products]
UniProt Synonym Gene Names
C21orf107; WDR9  [Similar Products]
UniProt Entry Name
BRWD1_HUMAN
NCBI Summary for BRWD1
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats, and the function of this protein is not known. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates 3 transcript variants diverging at the 3' ends. [provided by RefSeq]
UniProt Comments for BRWD1
WDR9: an ubiquitously expressed WD40 repeat protein that may be a transcriptional activator and be involved in chromatin remodeling. Interacts with SMARCA4. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Three alternatively spliced human isoforms have been described.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 21q22.2

Cellular Component: cytoplasm; nucleolus; nucleus

Biological Process: regulation of transcription from RNA polymerase II promoter; regulation of cell shape; transcription, DNA-dependent; cytoskeleton organization and biogenesis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-BRWD1 antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1 publications with BRWD1 and Necrosis
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