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anti-ZIC5 antibody :: Goat ZIC5 Polyclonal Antibody

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Catalog # MBS421347
Unit / Price
  0.1 mg  /  $300 +1 FREE 8GB USB
anti-ZIC5 antibody
Product Name

ZIC5, Polyclonal Antibody

Also Known As

Goat anti-ZIC5 Antibody

Product Synonym Names
ZIC5; zinc finger protein of the cerebellum 5; zinc family member 5 protein; Zic family member 5 (odd-paired homolog, Drosophila); ZIC5 antibody; zinc finger protein of the cerebellum 5 antibody; zinc family member 5 protein antibody; Zic family member 5 (odd-paired homolog; Drosophila) antibody
Antibody/Peptide Pairs
ZIC5 peptide (MBS425208) is used for blocking the activity of ZIC5 antibody (MBS421347)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
663
Immunogen Sequence
EIYGNPEVVR TIH
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence C-EIYGNPEVVRTIH, from the C Terminus of the protein sequence according to NP_149123.2.
Epitope
C Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-ZIC5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ZIC5 antibody
Peptide ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-ZIC5 antibody
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Immunohistochemistry: In paraffin embedded Human Small Intestine shows nuclear staining. Recommended concentration, 3-5ug/ml.
Western Blot: Preliminary experiments gave an approx 45kDa band in human brain lysates at 1ug/ml. This band was successfully blocked by incubation with the immunising peptide. Please note that currently we cannot find an explanation in the literature for the band we observe given the predicted size of approx.73kDda according to NP_149123.
NCBI/Uniprot data below describe general gene information for ZIC5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
68,448 Da
NCBI Official Full Name
zinc finger protein ZIC 5
NCBI Official Synonym Full Names
Zic family member 5
NCBI Official Symbol
NCBI Protein Information
zinc finger protein ZIC 5
UniProt Protein Name
Zinc finger protein ZIC 5
UniProt Synonym Protein Names
Zinc finger protein of the cerebellum 5
Protein Family
UniProt Gene Name
UniProt Entry Name
ZIC5_HUMAN
NCBI Summary for ZIC5
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 2, a related family member on chromosome 13. [provided by RefSeq, Jul 2008]
UniProt Comments for ZIC5
ZIC5: Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA. Belongs to the GLI C2H2-type zinc-finger protein family.

Protein type: Motility/polarity/chemotaxis; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 13q32.3

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding

Biological Process: cell differentiation; nervous system development
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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