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anti-CDKL2 antibody :: Rabbit CDKL2 Polyclonal Antibody

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Catalog # MBS8240611
Unit / Price
  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

CDKL2, Polyclonal Antibody

Also Known As

Anti-CDKL2 Antibody

Product Synonym Names
Cyclin-dependent kinase-like 2; Protein kinase p56 KKIAMRE; Serine/threonine-protein kinase KKIAMRE
Antibody/Peptide Pairs
CDKL2 peptide (MBS8209055) is used for blocking the activity of CDKL2 antibody (MBS8240611)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
493
OMIM
603442
3D Structure
ModBase 3D Structure for Q92772
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Monkey
Specificity
Recognizes endogenous levels of CDKL2 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CDKL2. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-CDKL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CDKL2 antibody
Rabbit polyclonal antibody to CDKL2
Applications Tested/Suitable for anti-CDKL2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CDKL2 antibody
WB (1/500 - 1/1000), IHC (1/100 - 1/200)

Western Blot (WB) of anti-CDKL2 antibody
Western blot analysis of CDKL2 expression in SHSYSY (A) whole cell lysates.
anti-CDKL2 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-CDKL2 antibody
Immunohistochemical analysis of CDKL2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
anti-CDKL2 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CDKL2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,019 Da
NCBI Official Full Name
cyclin-dependent kinase-like 2
NCBI Official Synonym Full Names
cyclin-dependent kinase-like 2 (CDC2-related kinase)
NCBI Official Symbol
CDKL2  [Similar Products]
NCBI Official Synonym Symbols
P56; KKIAMRE
  [Similar Products]
NCBI Protein Information
cyclin-dependent kinase-like 2
UniProt Protein Name
Cyclin-dependent kinase-like 2
UniProt Synonym Protein Names
Protein kinase p56 KKIAMRE; Serine/threonine-protein kinase KKIAMRE
Protein Family
UniProt Gene Name
CDKL2  [Similar Products]
UniProt Entry Name
CDKL2_HUMAN
NCBI Summary for CDKL2
This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus. [provided by RefSeq, Jul 2008]
UniProt Comments for CDKL2
CDKL2: a protein kinase of the CDKL family. Accumulates primarily in the cytoplasm, with a lower level in the nucleus.

Protein type: Protein kinase, Ser/Thr (non-receptor); Protein kinase, CMGC; EC 2.7.11.22; Kinase, protein; Cell cycle regulation; CMGC group; CDKL family

Chromosomal Location of Human Ortholog: 4q21.1

Cellular Component: nucleoplasm; centrosome; cytoplasm; nucleus

Molecular Function: cyclin-dependent protein kinase activity; ATP binding; protein kinase activity

Biological Process: regulation of cell cycle; signal transduction; protein amino acid phosphorylation; sex differentiation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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