• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-CD247 antibody :: CD247 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS8221871
Unit / Price
Scan QR to view Datasheet
  0.03 mL  /  $155 +1 FREE 8GB USB
  0.1 mL  /  $220 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Western Blot (WB)
Product Name

CD247, Polyclonal Antibody

Popular Item
Full Product Name

Anti-CD247 Antibody

Product Synonym Names
CD3Z; T3Z; TCRZ; T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD247
Antibody/Peptide Pairs
CD247 peptide (MBS8213088) is used for blocking the activity of CD247 antibody (MBS8221871)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
186780
3D Structure
ModBase 3D Structure for P20963
Clonality
Polyclonal
Species Reactivity
Human, Mouse, Rat, Monkey, Porcine, Rabbit
Specificity
Recognizes endogenous levels of CD247 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Source
Rabbit
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD247. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-CD247 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD247 antibody
Rabbit polyclonal antibody to CD247
Applications Tested/Suitable for anti-CD247 antibody
Western Blot (WB)
Application Notes for anti-CD247 antibody
WB (1/500 - 1/1000)

Western Blot (WB) of anti-CD247 antibody
Western blot analysis of CD247 expression in Jurkat (A), NS-1 (B), PC12 (C) whole cell lysates.
anti-CD247 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CD247. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
– Da
NCBI Official Full Name
T-cell surface glycoprotein CD3 zeta chain isoform 2
NCBI Official Synonym Full Names
CD247 molecule
NCBI Official Symbol
CD247  [Similar Products]
NCBI Official Synonym Symbols
T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3-ZETA
  [Similar Products]
NCBI Protein Information
T-cell surface glycoprotein CD3 zeta chain
UniProt Protein Name
T-cell surface glycoprotein CD3 zeta chain
UniProt Synonym Protein Names
T-cell receptor T3 zeta chain; CD_antigen: CD247
UniProt Gene Name
CD247  [Similar Products]
UniProt Synonym Gene Names
CD3Z; T3Z; TCRZ  [Similar Products]
UniProt Entry Name
CD3Z_HUMAN
NCBI Summary for CD247
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for CD247
CD3Z: a T cell surface glycoprotein that is a component of the T cell antigen receptor. Plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the CD3-epsilon results in impaired immune response. Two alternatively spliced isoforms have been described.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q24.2

Cellular Component: T cell receptor complex; cytoplasm; integral to membrane; plasma membrane; alpha-beta T cell receptor complex

Molecular Function: identical protein binding; protein binding; transmembrane receptor activity; protein homodimerization activity

Biological Process: regulation of immune response; viral reproduction; T cell costimulation; innate immune response; T cell receptor signaling pathway; regulation of defense response to virus by virus

Disease: Immunodeficiency 25
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000