NP_000917.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 99 kDa Predicted: 99 kDa
NCBI Official Full Name
progesterone receptor isoform B
NCBI Official Synonym Full Names
progesterone receptor
NCBI Official Synonym Symbols
NCBI Protein Information
progesterone receptor
UniProt Protein Name
Progesterone receptor
UniProt Synonym Protein Names
Nuclear receptor subfamily 3 group C member 3
UniProt Synonym Gene Names
NCBI Summary for PGR
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]
UniProt Comments for PGR
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as transcriptional activator or repressor.
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Products associated with anti-PGR antibody
Pathways associated with anti-PGR antibody
Diseases associated with anti-PGR antibody
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