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anti-ABCB11 antibody :: Rabbit anti-Human, Mouse ABCB11 Polyclonal Antibody

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Catalog # MBS9429110
Unit / Price
  0.05 mL  /  $200 +1 FREE 8GB USB
  0.1 mL  /  $255 +1 FREE 8GB USB
Western Blot (WB)
Product Name

ABCB11, Polyclonal Antibody

Also Known As

ABCB11 (Phospho-Ser690) Antibody

Product Synonym Names
ABC member 16, MDR/TAP subfamily; ABC16; ABCB1; Abcb11; ABCBB_HUMAN; ATP binding cassette sub family B (MDR/TAP) member 11; ATP binding cassette sub family B member 11; ATP-binding cassette sub-family B member 11; Bile salt export pump; BRIC2; Bsep; PFIC 2; PFIC2; PGY4; progressive familial intrahepatic cholestasis 2; Sister of P glycoprotein; Spgp;
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1321
OMIM
AF091582 mRNA
3D Structure
ModBase 3D Structure for O95342
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Specificity
Phospho-ABCB11 (Phospho-Ser690) Antibody detects endogenous levels of ABCB11 only when phosphorylated at Ser690
Purity/Purification
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (lot specific)
Immunogen
A synthesized peptide derived from human ABCB11 around the phosphorylation site of Ser690
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.
Other Notes
Small volumes of anti-ABCB11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-ABCB11 antibody
Applications Tested/Suitable for anti-ABCB11 antibody
Western Blot (WB)
Application Notes for anti-ABCB11 antibody
WB: 1:500-1:2000

Western Blot (WB) of anti-ABCB11 antibody
Western blot analysis of extracts of mouse liver tissue sample, using Phospho-ABCB11 (Ser690) Antibody.(12958)
anti-ABCB11 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for ABCB11. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
146
NCBI Official Full Name
bile salt export pump
NCBI Official Synonym Full Names
ATP binding cassette subfamily B member 11
NCBI Official Symbol
ABCB11  [Similar Products]
NCBI Official Synonym Symbols
BSEP; PGY4; SPGP; ABC16; BRIC2; PFIC2; PFIC-2
  [Similar Products]
NCBI Protein Information
bile salt export pump
UniProt Protein Name
Bile salt export pump
UniProt Synonym Protein Names
ATP-binding cassette sub-family B member 11
Protein Family
UniProt Gene Name
ABCB11  [Similar Products]
UniProt Synonym Gene Names
NCBI Summary for ABCB11
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCB11
Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-ABCB11 antibody
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