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anti-APIP antibody :: Rabbit anti-Human, Mouse APIP Polyclonal Antibody

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Catalog # MBS7044091
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

APIP, Polyclonal Antibody

Popular Item
Full Product Name

APIP Antibody

Product Synonym Names
Methylthioribulose-1-phosphate dehydratase; APAF1-interacting protein; APIP
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q96GX9
Species Reactivity
Human, Mouse
Antigen Affinity Purified
Recombinant human Methylthioribulose-1-phosphate dehydratase protein (1-242AA)
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-66318 / sc-66319 / sc-292256
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-APIP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-APIP antibody
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
Applications Tested/Suitable for anti-APIP antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-APIP antibody
Western blot
All lanes:  APIPantibody at 1.85ug/ml
Lane 1 : Mouse heart tissue
Lane 2 : Mouse kidney tissue
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 28,23 kDa
Observed band size: 27 kDa

anti-APIP antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-APIP antibody
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using MBS7044091 at dilution 1:100
anti-APIP antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-APIP antibody
Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS7044091 at dilution 1:100
anti-APIP antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for APIP. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
22,858 Da
NCBI Official Full Name
methylthioribulose-1-phosphate dehydratase
NCBI Official Synonym Full Names
APAF1 interacting protein
NCBI Official Symbol
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
methylthioribulose-1-phosphate dehydratase
UniProt Protein Name
Methylthioribulose-1-phosphate dehydratase
UniProt Synonym Protein Names
APAF1-interacting protein
UniProt Gene Name
UniProt Synonym Gene Names
MTRu-1-P dehydratase; hAPIP  [Similar Products]
UniProt Entry Name
NCBI Summary for APIP
APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury (Cho et al., 2004 [PubMed 15262985]).[supplied by OMIM, Dec 2008]
UniProt Comments for APIP
MMRP19: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P). Has an anti-apoptotic function and prevents muscle ischemic damage. Inhibits the cytochrome c- dependent and APAF1-mediated cell death. Belongs to the aldolase class II family. MtnB subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Amino Acid Metabolism - cysteine and methionine; EC

Chromosomal Location of Human Ortholog: 11p13

Molecular Function: identical protein binding; protein binding

Biological Process: methionine salvage; negative regulation of apoptosis
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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