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anti-APOBEC1 antibody :: Goat APOBEC1 Polyclonal Antibody

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Catalog # MBS421886
Unit / Price
  0.1 mg  /  $300 +1 FREE 8GB USB
Western Blot (WB)
Product Name

APOBEC1, Polyclonal Antibody

Full Product Name

Goat anti-APOBEC1 Antibody

Product Synonym Names
APOBEC1; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1; APOBEC-1; BEDP; CDAR1; HEPR; apolipoprotein B mRNA editing enzyme; apolipoprotein B mRNA editing enzyme complex-1; APOBEC1 antibody; apolipoprotein B mRNA editing enzyme; catalytic polypeptide 1 antibody; APOBEC-1 antibody; BEDP antibody; CDAR1 antibody; HEPR antibody; apolipoprotein B mRNA editing enzyme antibody; apolipoprotein B mRNA editing enzyme complex-1 antibody
Antibody/Peptide Pairs
APOBEC1 peptide (MBS425185) is used for blocking the activity of APOBEC1 antibody (MBS421886)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
DVFYDPRELR KEAC
OMIM
600130
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Mouse; Expected from sequence similarity: Human, Mouse
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (lot specific)
Immunogen
Peptide with sequence DVFYDPRELRKEAC, from the internal region (near N Terminus) of the protein sequence according to NP_001635.2.
Epitope
Internal region (near N Terminus)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-APOBEC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-APOBEC1 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-APOBEC1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx.28kDa band observed in Mouse Spleen lysates (calculated MW of 28.2kDa according to Human NP_001635.2 and 27.5kDa acccording to Mouse NP_112436.1). Recommended concentration: 1-3ug/ml.

Western Blot (WB) of anti-APOBEC1 antibody
(1ug/ml) staining of Mouse Spleen lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-APOBEC1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for APOBEC1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28,192 Da
NCBI Official Full Name
C->U-editing enzyme APOBEC-1 isoform a
NCBI Official Synonym Full Names
apolipoprotein B mRNA editing enzyme catalytic subunit 1
NCBI Official Symbol
APOBEC1  [Similar Products]
NCBI Official Synonym Symbols
BEDP; HEPR; CDAR1; APOBEC-1
  [Similar Products]
NCBI Protein Information
C->U-editing enzyme APOBEC-1
UniProt Protein Name
C->U-editing enzyme APOBEC-1
UniProt Synonym Protein Names
Apolipoprotein B mRNA-editing enzyme 1; HEPR; mRNA(cytosine(6666)) deaminase 1
UniProt Gene Name
APOBEC1  [Similar Products]
UniProt Entry Name
ABEC1_HUMAN
NCBI Summary for APOBEC1
This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015]
UniProt Comments for APOBEC1
APOBEC1: apolipoprotein B mRNA editing enzyme. Responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. Expressed exclusively in the small intestine.

Protein type: Cell cycle regulation; RNA processing; Hydrolase; RNA-binding; EC 3.5.4.-

Chromosomal Location of Human Ortholog: 12p13.1

Cellular Component: cytoplasm; nucleoplasm

Molecular Function: AU-rich element binding; cytidine deaminase activity; cytosine deaminase activity; enzyme activator activity; mRNA binding; protein binding; protein domain specific binding; ribonucleoprotein binding; RNA binding; zinc ion binding

Biological Process: cellular response to insulin stimulus; cytidine deamination; cytidine to uridine editing; defense response to virus; lipid metabolic process; lipoprotein biosynthetic process; lipoprotein transport; mRNA modification; mRNA processing; mRNA stabilization; positive regulation of catalytic activity; regulation of cell proliferation; response to calcium ion; response to drug; response to ethanol; response to gamma radiation; response to osmotic stress; response to zinc ion; RNA processing
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-APOBEC1 antibody
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >12 publications with APOBEC1 and Intestine
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