• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-ARHGDIG antibody :: Rabbit anti-Human, Mouse ARHGDIG Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS7044415
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

ARHGDIG, Polyclonal Antibody

Popular Item
Also Known As

ARHGDIG Antibody

Product Synonym Names
Rho GDP-dissociation inhibitor 3Rho GDI 3; Rho-GDI gamma; ARHGDIG
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
225
OMIM
602844
3D Structure
ModBase 3D Structure for Q99819
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Rho GDP-dissociation inhibitor 3 protein
Conjugate
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-6910
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-ARHGDIG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ARHGDIG antibody
Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.
Applications Tested/Suitable for anti-ARHGDIG antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Western Blot (WB) of anti-ARHGDIG antibody
Western blot
All lanes :ARHGDIG antibody at 2 ug/ml
Lane 1 : Mouse brain tissue
Lane 2 : Mouse lung tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 25 kDa
Observed band size: 25,50 kDa

anti-ARHGDIG antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ARHGDIG antibody
Immunohistochemistry of paraffin-embedded human brain tissue using MBS7044415 at dilution of 1:100
anti-ARHGDIG antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-ARHGDIG antibody
Immunohistochemistry of paraffin-embedded human placenta tissue using MBS7044415 at dilution of 1:100
anti-ARHGDIG antibody Immunohistochemistry (IHC) (IHC) image
Immunofluorescence (IF) of anti-ARHGDIG antibody
Immunofluorescent analysis of mcf-7 cells using MBS7044415 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-ARHGDIG antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for ARHGDIG. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,098 Da
NCBI Official Full Name
rho GDP-dissociation inhibitor 3
NCBI Official Synonym Full Names
Rho GDP dissociation inhibitor gamma
NCBI Official Symbol
ARHGDIG  [Similar Products]
NCBI Official Synonym Symbols
RHOGDI-3
  [Similar Products]
NCBI Protein Information
rho GDP-dissociation inhibitor 3
UniProt Protein Name
Rho GDP-dissociation inhibitor 3
UniProt Synonym Protein Names
Rho-GDI gamma
UniProt Gene Name
ARHGDIG  [Similar Products]
UniProt Synonym Gene Names
Rho GDI 3  [Similar Products]
UniProt Entry Name
GDIR3_HUMAN
NCBI Summary for ARHGDIG
The GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases by inhibiting the exchange of GDP for GTP. See ARHGDIB (MIM 602843).[supplied by OMIM, Nov 2010]
UniProt Comments for ARHGDIG
RhoGDI gamma: Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post- translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP. Belongs to the Rho GDI family.

Protein type: Cell adhesion; G protein regulator, misc.; Motility/polarity/chemotaxis; Inhibitor

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: cytoplasmic membrane-bound vesicle; cytosol

Molecular Function: protein binding

Biological Process: negative regulation of cell adhesion; regulation of small GTPase mediated signal transduction; Rho protein signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000