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anti-BBS1 antibody :: Rabbit anti-Human, Mouse BBS1 Polyclonal Antibody

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Catalog # MBS7050799
Unit / Price
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  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

BBS1, Polyclonal Antibody

Popular Item
Full Product Name

BBS1 Antibody

Product Synonym Names
Bardet-Biedl syndrome 1 protein; BBS2-like protein 2; BBS1; BBS2L2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
AF503941 mRNA
3D Structure
ModBase 3D Structure for Q8NFJ9
Species Reactivity
Human, Mouse
>95%, Protein G purified
Recombinant Human Bardet-Biedl syndrome 1 protein (217-417AA)
0.03% Proclin 300
50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-49789 / sc-49790 / sc-49791
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-BBS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-BBS1 antibody
The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
Applications Tested/Suitable for anti-BBS1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-BBS1 antibody
WB: 1: 500-1: 5000
IHC: 1: 20-1: 200
IF: 1: 50-1: 200

Western Blot (WB) of anti-BBS1 antibody
Western Blot
Positive WB detected in:Mouse lung tissue
All lanes: BBS1 antibody at 1ug/ml
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 66,70,50 kDa
Observed band size: 66 kDa

anti-BBS1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-BBS1 antibody
Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7050799 at dilution of 1:100
anti-BBS1 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-BBS1 antibody
Immunohistochemistry of paraffin-embedded human liver tissue using MBS7050799 at dilution of 1:100
anti-BBS1 antibody Immunohistochemistry (IHC) (IHC) image
Immunofluorescence (IF) of anti-BBS1 antibody
Immunofluorescent analysis of HepG2 cells using MBS7050799 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-BBS1 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for BBS1. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
49,006 Da
NCBI Official Full Name
Bardet-Biedl syndrome 1 protein
NCBI Official Synonym Full Names
Bardet-Biedl syndrome 1
NCBI Official Symbol
NCBI Official Synonym Symbols
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NCBI Protein Information
Bardet-Biedl syndrome 1 protein
UniProt Protein Name
Bardet-Biedl syndrome 1 protein
UniProt Synonym Protein Names
BBS2-like protein 2
UniProt Gene Name
UniProt Synonym Gene Names
BBS2L2  [Similar Products]
UniProt Entry Name
NCBI Summary for BBS1
Mutations in this gene have been observed in patients with the major form (type 1) of Bardet-Biedl syndrome. The encoded protein may play a role in eye, limb, cardiac and reproductive system development. [provided by RefSeq, Jul 2008]
UniProt Comments for BBS1
BBS1: defects in BBS1 are a cause of Bardet-Biedl syndrome type (BBS). BBS is characterized by usually severe pigmentary retinopathy, early onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation. Two alternatively splioced isoforms have been reported.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: axoneme; centrosome; cytosol

Molecular Function: patched binding; protein binding; smoothened binding

Biological Process: Golgi to plasma membrane protein transport; photoreceptor cell maintenance; retinal homeostasis

Disease: Bardet-biedl Syndrome 1
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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