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anti-BMP-8 antibody :: Rabbit anti-Human, Mouse BMP-8 Polyclonal Antibody

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Catalog # MBS9608826
Unit / Price
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  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

BMP-8, Polyclonal Antibody

Popular Item
Full Product Name

BMP-8 Antibody

Product Synonym Names
BMP-8; BMP-8B; BMP8; Bmp8b; BMP8B_HUMAN; bone morphogenetic protein 8 (osteogenic protein 2); Bone morphogenetic protein 8; Bone morphogenetic protein 8B; dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)); OP-2; OP2; Osteogenic protein 2; BMP-8A; BMP8; Bmp8a; BMP8A_HUMAN; Bone morphogenetic protein 8A; FLJ14351; FLJ45264; OP 2; Osteogenic protein 2
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P34820
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Specificity
BMP-8 antibody detects endogenous levels of total BMP-8
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human BMP-8
Subcellular Location
Secreted.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-BMP-8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-BMP-8 antibody
Function: Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity).
Subunit Structure: Homodimer; disulfide-linked.
Similarity: Belongs to the TGF-beta family.
Applications Tested/Suitable for anti-BMP-8 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-BMP-8 antibody
WB: 1:1000-3000
IHC: 1:200

Western Blot (WB) of anti-BMP-8 antibody
Western blot analysis of BMP-8 using COS7 whole cell lysates
anti-BMP-8 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-BMP-8 antibody
MBS9608826 at 1/100 staining Human pancreas tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
anti-BMP-8 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for BMP-8. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 44 kDa
Predicted: 45 kDa
NCBI Official Full Name
bone morphogenetic protein 8B preproprotein
NCBI Official Synonym Full Names
bone morphogenetic protein 8b
NCBI Official Symbol
BMP8B  [Similar Products]
NCBI Official Synonym Symbols
OP2; BMP8
  [Similar Products]
NCBI Protein Information
bone morphogenetic protein 8B
UniProt Protein Name
Bone morphogenetic protein 8B
UniProt Synonym Protein Names
Osteogenic protein 2; OP-2
UniProt Gene Name
BMP8B  [Similar Products]
UniProt Synonym Gene Names
BMP8; BMP-8; BMP-8B; OP-2  [Similar Products]
NCBI Summary for BMP-8
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]
UniProt Comments for BMP-8
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-BMP-8 antibody
 Reference Product  PubMed Publications
 BMP4 antibody  >15 publications with BMP-8 and BMP4
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