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anti-C9 antibody :: anti-Human, Mouse C9 Polyclonal Antibody

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Catalog # MBS9125401
Unit / Price
  0.05 mL  /  $230 +1 FREE 8GB USB
  0.1 mL  /  $305 +1 FREE 8GB USB
  0.2 mL  /  $460 +1 FREE 8GB USB
Western Blot (WB)
Product Name

C9, Polyclonal Antibody

Popular Item
Full Product Name

C9

Product Synonym Names
ARMD15, C9D
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
phenotype 615591
3D Structure
ModBase 3D Structure for P02748
Clonality
Polyclonal
Isotype
IgG
Species Reactivity
Human, Mouse
Purity/Purification
Affinity purification
Source
Rabbit
Immunogen
Recombinant funsion protein containing a sequence corresponding to amino acids 22-265 of human C9 (NP_001728.1)
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Calculated MW
63 kDa
Observed MW
70 kDa
Preparation and Storage
Store at -20°C. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-C9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-C9 antibody
This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency.
Product Categories/Family for anti-C9 antibody
Applications Tested/Suitable for anti-C9 antibody
Western Blot (WB)
Application Notes for anti-C9 antibody
1:500- 1:2000

Western Blot (WB) of anti-C9 antibody
Western blot analysis of extracts of mouse liver, using C9 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
anti-C9 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for C9. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Complement component C9
NCBI Official Synonym Full Names
complement component 9
NCBI Official Symbol
NCBI Official Synonym Symbols
C9D; ARMD15
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NCBI Protein Information
complement component C9
UniProt Protein Name
Complement component C9
Protein Family
UniProt Gene Name
UniProt Entry Name
CO9_HUMAN
NCBI Summary for C9
This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009]
UniProt Comments for C9
C9: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. Defects in C9 are a cause of complement component 9 deficiency (C9D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family.

Protein type: Extracellular matrix; Membrane protein, multi-pass; Membrane protein, integral; Apoptosis

Chromosomal Location of Human Ortholog: 5p14-p12

Cellular Component: membrane attack complex; integral to plasma membrane; cytoplasm; plasma membrane; extracellular region

Biological Process: complement activation, alternative pathway; regulation of complement activation; innate immune response; hemolysis by symbiont of host red blood cells; complement activation, classical pathway

Disease: Macular Degeneration, Age-related, 15; Complement Component 9 Deficiency
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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