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anti-CD1C antibody :: Rabbit anti-Human, Mouse CD1C Polyclonal Antibody

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Catalog # MBS7051829
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

CD1C, Polyclonal Antibody

Popular Item
Also Known As

CD1C Antibody

Product Synonym Names
T-cell surface glycoprotein CD1c; CD1c; CD1C
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS7051829 Technical Datasheet
Immunogen Sequence Length
333
OMIM
3D Structure
ModBase 3D Structure for P29017
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Immunogen
Recombinant Human T-cell surface glycoprotein CD1c protein (18-302AA)
Conjugation
Non-conjugated
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-CD1C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD1C antibody
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Applications Tested/Suitable for anti-CD1C antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-CD1C antibody
WB: 1:500-1:5000
IF: 1:50-1:200

Western Blot (WB) of anti-CD1C antibody
Western Blot
Positive WB detected in: Mouse heart tissue
All lanes: CD1C antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 38 KDa
Observed band size: 38 KDa

anti-CD1C antibody Western Blot (WB) (WB) image
Immunofluorescence (IF) of anti-CD1C antibody
Immunofluorescent analysis of A549 cells using MBS7051829 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-CD1C antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for CD1C. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,654 Da
NCBI Official Full Name
T-cell surface glycoprotein CD1c
NCBI Official Synonym Full Names
CD1c molecule
NCBI Official Symbol
NCBI Official Synonym Symbols
R7; CD1; CD1A; BDCA1
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NCBI Protein Information
T-cell surface glycoprotein CD1c
UniProt Protein Name
T-cell surface glycoprotein CD1c
UniProt Synonym Protein Names
CD_antigen: CD1c
UniProt Gene Name
NCBI Summary for CD1C
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008]
UniProt Comments for CD1C
CD1C: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: beta-2-microglobulin binding; endogenous lipid antigen binding; exogenous lipid antigen binding; glycolipid binding

Biological Process: antigen processing and presentation, exogenous lipid antigen via MHC class Ib; regulation of immune response; T cell activation during immune response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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