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anti-CNN2 antibody :: Rabbit anti-Human, Mouse CNN2 Polyclonal Antibody

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Catalog # MBS7051100
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

CNN2, Polyclonal Antibody

Popular Item
Full Product Name

CNN2 Antibody

Product Synonym Names
Calponin-2; Calponin H2; smooth muscle; Neutral calponin; CNN2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
D83735 mRNA
3D Structure
ModBase 3D Structure for Q99439
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Immunogen
Recombinant Human Calponin-2 protein (2-309AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Non-conjugated
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-16607 / sc-16608
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-CNN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CNN2 antibody
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Applications Tested/Suitable for anti-CNN2 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-CNN2 antibody
WB: 1: 2000-1: 10000
IF: 1: 50-1: 200

Western Blot (WB) of anti-CNN2 antibody
Western Blot
Positive WB detected in:Hela whole cell lysate,Mouse liver tissue,Mouse lung tissue,Mouse kidney tissue,Mouse brain tissue,Mouse skeletal muscle tissue
All lanes: CNN2 antibody at 2.5ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 34,30 kDa
Observed band size: 34 kDa

anti-CNN2 antibody Western Blot (WB) (WB) image
Immunofluorescence (IF) of anti-CNN2 antibody
Immunofluorescent analysis of HepG2 cells using MBS7051100 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-CNN2 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for CNN2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
29,500 Da
NCBI Official Full Name
calponin-2 isoform c
NCBI Official Synonym Full Names
calponin 2
NCBI Official Symbol
NCBI Protein Information
calponin-2
UniProt Protein Name
Calponin-2
UniProt Synonym Protein Names
Calponin H2, smooth muscle; Neutral calponin
Protein Family
UniProt Gene Name
UniProt Entry Name
CNN2_HUMAN
NCBI Summary for CNN2
The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
UniProt Comments for CNN2
calponin 2: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Belongs to the calponin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Actin-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cell-cell adherens junction; cytoskeleton; focal adhesion; intercellular junction; membrane; stress fiber

Biological Process: cytoskeleton organization and biogenesis; regulation of actin filament-based process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-CNN2 antibody
 Reference Product  PubMed Publications
 ACTB antibody  >1 publications with CNN2 and ACTB
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