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anti-CNTNAP1 antibody :: Rabbit anti-Human, Mouse CNTNAP1 Polyclonal Antibody

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Catalog # MBS9609732
Unit / Price
  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Western Blot (WB)
Product Name

CNTNAP1, Polyclonal Antibody

Popular Item
Also Known As

CNTNAP1 Antibody

Product Synonym Names
Caspr; Caspr1; CNTNAP; Cntnap1; CNTP1_HUMAN; Contactin associated protein 1; Contactin-associated protein 1; MHDNIV; NCP1; Neurexin 4; Neurexin IV; Neurexin-4; Nrxn4; p190; Paranodin
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1384
3D Structure
ModBase 3D Structure for P78357
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Specificity
CNTNAP1 antibody detects endogenous levels of total CNTNAP1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human CNTNAP1
Subcellular Location
Membrane.
Tissue Specificity
Predominantly expressed in brain. Weak expression detected in ovary, pancreas, colon, lung, heart, intestine and testis.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-CNTNAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CNTNAP1 antibody
Function: Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells.
Subunit Structure: Interacts with CNTN1/contactin in cis form.
Similarity: Belongs to the neurexin family.
Applications Tested/Suitable for anti-CNTNAP1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CNTNAP1 antibody
WB: 1:1000-3000

Western Blot (WB) of anti-CNTNAP1 antibody
Western blot analysis of CNTNAP1 using COS7 whole cell lysates
anti-CNTNAP1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CNTNAP1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 156 kDa
Predicted: 157 kDa
NCBI Official Full Name
contactin-associated protein 1
NCBI Official Synonym Full Names
contactin associated protein 1
NCBI Official Symbol
CNTNAP1  [Similar Products]
NCBI Official Synonym Symbols
P190; CASPR; NRXN4; CNTNAP
  [Similar Products]
NCBI Protein Information
contactin-associated protein 1
UniProt Protein Name
Contactin-associated protein 1
UniProt Synonym Protein Names
Neurexin IV; Neurexin-4; p190
UniProt Gene Name
CNTNAP1  [Similar Products]
UniProt Synonym Gene Names
CASPR; NRXN4; Caspr; Caspr1  [Similar Products]
NCBI Summary for CNTNAP1
The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. [provided by RefSeq, Jan 2009]
UniProt Comments for CNTNAP1
Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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