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anti-CUTL1 antibody :: Rabbit anti-Human, Mouse CUTL1 Polyclonal Antibody

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Catalog # MBS9601374
Unit / Price
  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

CUTL1, Polyclonal Antibody

Popular Item
Also Known As

CUTL1 Antibody

Product Synonym Names
CASP; CCAAT displacement protein; CDP; CDP/Cut; CDP1; Clox; COY1; Cut homeobox; Cut homolog; Cut like 1; Cut like homeobox 1; CUTL1; CUX; Cux/CDP; CUX1; Golgi integral membrane protein 6; GOLIM6; Homeobox protein cux 1; Nbla10317; p100; p110; p200; p75; Protein CASP; Putative protein product of Nbla10317
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1516
3D Structure
ModBase 3D Structure for P39880
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Specificity
CUTL1 antibody detects endogenous levels of total CUTL1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human CUTL1
Subcellular Location
Golgi Apparatus Membrane; Single-Pass Type IV Membrane Protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-CUTL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CUTL1 antibody
Description: Belongs to the CASP family. May be involved in intra-Golgi retrograde transport. Homodimer; disulfide-linked. Interacts with GOLGA5.
Function: Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator (By similarity).
Subunit Structure: Interacts with BANP. Interacts with SATB1 (via DNA-binding domains); the interaction inhibits the attachment of both proteins to DNA (By similarity).
Similarity: Belongs to the CUT homeobox family.
Applications Tested/Suitable for anti-CUTL1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CUTL1 antibody
WB: 1:500-1:2000

Western Blot (WB) of anti-CUTL1 antibody
Western blot analysis of CUTL1 expression in rat heart.
anti-CUTL1 antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-CUTL1 antibody
Western blot analysis of CUTL1 expression in K562 cells, The lane on the left is treated with the antigen-specific peptide.
anti-CUTL1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CUTL1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 164 kDa
Predicted: 165 kDa
NCBI Official Full Name
protein CASP isoform d
NCBI Official Synonym Full Names
cut like homeobox 1
NCBI Official Symbol
NCBI Official Synonym Symbols
CDP; CUX; p75; CASP; CDP1; COY1; Clox; p100; p110; p200; CUTL1; GOLIM6; CDP/Cut; Cux/CDP; Nbla10317
  [Similar Products]
NCBI Protein Information
protein CASP
UniProt Protein Name
Homeobox protein cut-like 1
UniProt Synonym Protein Names
CCAAT displacement protein; CDP; Homeobox protein cux-1
UniProt Gene Name
UniProt Synonym Gene Names
CUTL1; CDP  [Similar Products]
NCBI Summary for CUTL1
The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Feb 2011]
UniProt Comments for CUTL1
Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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