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anti-DNAJC19 antibody :: Rabbit anti-Human, Mouse DNAJC19 Polyclonal Antibody

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Catalog # MBS7044335
Unit / Price
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  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

DNAJC19, Polyclonal Antibody

Popular Item
Full Product Name

DNAJC19 Antibody

Product Synonym Names
Mitochondrial import inner membrane translocase subunit TIM14; DnaJ homolog subfamily C member 19; DNAJC19; TIM14; TIMM14
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
608977
3D Structure
ModBase 3D Structure for Q96DA6
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Mitochondrial import inner membrane translocase subunit TIM14 protein (1-116AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-DNAJC19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-DNAJC19 antibody
Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity).
Applications Tested/Suitable for anti-DNAJC19 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-DNAJC19 antibody
Western blot
All lanes: DNAJC19 antibody at 0.9 ug/ml
Lane 1: Mouse lung tissue
Lane 2: Mouse kidney tissue
Lane 3: A549 whole cell lysate
Lane 4: HL60 whole cell lysate
Lane 5: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 13,11 kDa
Observed band size: 12 kDa

anti-DNAJC19 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-DNAJC19 antibody
Immunohistochemistry of paraffin-embedded human brain tissue using MBS7044335 at dilution of 1:100
anti-DNAJC19 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-DNAJC19 antibody
Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7044335 at dilution of 1:100
anti-DNAJC19 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for DNAJC19. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
10,079 Da
NCBI Official Full Name
mitochondrial import inner membrane translocase subunit TIM14 isoform 2
NCBI Official Synonym Full Names
DnaJ heat shock protein family (Hsp40) member C19
NCBI Official Symbol
DNAJC19  [Similar Products]
NCBI Official Synonym Symbols
PAM18; TIM14; TIMM14
  [Similar Products]
NCBI Protein Information
mitochondrial import inner membrane translocase subunit TIM14
UniProt Protein Name
Mitochondrial import inner membrane translocase subunit TIM14
UniProt Synonym Protein Names
DnaJ homolog subfamily C member 19
UniProt Gene Name
DNAJC19  [Similar Products]
UniProt Synonym Gene Names
TIM14; TIMM14  [Similar Products]
UniProt Entry Name
TIM14_HUMAN
NCBI Summary for DNAJC19
The protein encoded by this gene is thought to be part of a complex involved in the ATP-dependent transport of transit peptide-containing proteins from the inner cell membrane to the mitochondrial matrix. Defects in this gene are a cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 2, 6, 10, 14 and 19. [provided by RefSeq, Jan 2012]
UniProt Comments for DNAJC19
DNAJC19: Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity. Defects in DNAJC19 are the cause of 3-methylglutaconic aciduria type 5 (MGA5); also known as dilated cardiomyopathy with ataxia (DCMA). MGA5 is an autosomal recessive disorder characterized by early-onset dilated cardiomyopathy, growth failure, cerebellar ataxia causing significant motor delays, testicular dysgenesis, growth failure, and significant increases in urine organic acids, particularly 3-methylglutaconic acid and 3-methylglutaric acid. Belongs to the TIM14 family.

Protein type: Membrane protein, integral; Chaperone; Mitochondrial

Chromosomal Location of Human Ortholog: 3q26.33

Cellular Component: mitochondrial inner membrane; mitochondrion; protein complex

Molecular Function: protein binding

Biological Process: genitalia development; visual perception

Disease: 3-methylglutaconic Aciduria, Type V
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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