• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-ELAVL3 antibody :: Rabbit ELAVL3 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS2528867
Unit / Price
  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Product Name

ELAVL3, Polyclonal Antibody

Popular Item
Also Known As

ELAVL3 Polyclonal Antibody

Product Synonym Names
HUC; HUCL; PLE21
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
360
OMIM
603458
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Affinity purification
Concentration
1.3mg/mL (lot specific)
Immunogen
Synthetic peptide of human ELAVL3
Calculated Molecular Weight
40kDa
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C , Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-ELAVL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ELAVL3 antibody
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Applications Tested/Suitable for anti-ELAVL3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ELAVL3 antibody
WB: 1:200-1:1000
IHC: 1:25-1:100

Western Blot (WB) of anti-ELAVL3 antibody
Western Blot analysis of Human fetal brain tissue using ELAVL3 Polyclonal Antibody at dilution of 1:350
anti-ELAVL3 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ELAVL3 antibody
Immunohistochemistry of paraffin-embedded Human colon cancer using ELAVL3 Polyclonal Antibody at dilution of 1:20
anti-ELAVL3 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-ELAVL3 antibody
Immunohistochemistry of paraffin-embedded Human liver cancer using ELAVL3 Polyclonal Antibody at dilution of 1:20
anti-ELAVL3 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ELAVL3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,865 Da
NCBI Official Full Name
ELAV-like protein 3 isoform 2
NCBI Official Synonym Full Names
ELAV like neuron-specific RNA binding protein 3
NCBI Official Symbol
ELAVL3  [Similar Products]
NCBI Official Synonym Symbols
HUC; HUCL; PLE21
  [Similar Products]
NCBI Protein Information
ELAV-like protein 3; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); hu-antigen C; paraneoplastic cerebellar degeneration-associated antigen; paraneoplastic limbic encephalitis antigen 21
UniProt Protein Name
ELAV-like protein 3
UniProt Synonym Protein Names
Hu-antigen C; HuC; Paraneoplastic cerebellar degeneration-associated antigen; Paraneoplastic limbic encephalitis antigen 21
Protein Family
UniProt Gene Name
ELAVL3  [Similar Products]
UniProt Synonym Gene Names
HUC; PLE21; HuC  [Similar Products]
UniProt Entry Name
ELAV3_HUMAN
NCBI Summary for ELAVL3
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for ELAVL3
ELAVL3: Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3. May be involved in neuronal differentiation and maintenance. Belongs to the RRM elav family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 19p13.2

Molecular Function: nucleotide binding; AU-rich element binding

Biological Process: nervous system development; cell differentiation
Research Articles on ELAVL3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000