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anti-FNDC5 antibody :: Rabbit FNDC5 Polyclonal Antibody

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Catalog # MBS769410
Unit / Price
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  0.1 mg  /  $290 +1 FREE 8GB USB
Product Name

FNDC5, Polyclonal Antibody

Popular Item
Full Product Name

FNDC5 Rabbit Polyclonal

Product Synonym Names
FNDC5, FRCP2, Irisin
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS769410 Technical Datasheet
OMIM
611906
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse; other species are not tested.
Specificity
Please decide the specificity by homology
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Immunogen
Fibronectin type III domain containing 5
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Calculated MW
20 kDa
Preparation and Storage
Store at -20°C for 24 months (Avoid repeated freeze / thaw cycles.)
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-FNDC5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FNDC5 antibody
Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue.
Applications Tested/Suitable for anti-FNDC5 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Application Notes for anti-FNDC5 antibody
WB : 1:200-1:2000
IP :1:200-1:100
IHC : 1:20-1:200

Immunohistochemistry of anti-FNDC5 antibody
Immunohistochemistry of paraffin-embedded human skeletal muscle slide using MBS769410( FNDC5 Antibody) at dilution of 1:50
anti-FNDC5 antibody Immunohistochemistry (IHC) image
mouse placenta tissue were subjected to SDS PAGE followed by western blot with MBS769410 (FNDC5 antibody) at dilution of 1:1000
anti-FNDC5 antibody SDS-PAGE image
NCBI/Uniprot data below describe general gene information for FNDC5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
fibronectin type III domain-containing protein 5 isoform 2 preproprotein
NCBI Official Synonym Full Names
fibronectin type III domain containing 5
NCBI Official Symbol
FNDC5  [Similar Products]
NCBI Official Synonym Symbols
FRCP2; irisin
  [Similar Products]
NCBI Protein Information
fibronectin type III domain-containing protein 5
UniProt Protein Name
Fibronectin type III domain-containing protein 5
UniProt Synonym Protein Names
Fibronectin type III repeat-containing protein 2
UniProt Gene Name
FNDC5  [Similar Products]
UniProt Synonym Gene Names
FRCP2  [Similar Products]
UniProt Entry Name
FNDC5_HUMAN
NCBI Summary for FNDC5
This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
UniProt Comments for FNDC5
FNDC5: Irisin: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p35.1

Cellular Component: endoplasmic reticulum; extracellular region; integral to membrane; peroxisomal membrane; plasma membrane

Molecular Function: hormone activity

Biological Process: response to muscle activity
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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