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Chicken anti-Human, Mouse Fox3 Polyclonal Antibody

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Catalog # MBS645197
Unit / Price
  0.1 mL  /  $420 +1 FREE 8GB USB
anti-Fox3 antibody
Product Name

Fox3, Polyclonal Antibody

Also Known As

Fox3 (Fox-3, Fox-1 Homolog C, Hexaribonucleotide-binding Protein 3, Hrnbp3, Neuronal Nuclei, NeuN, RNA Binding Protein Fox-1 Homolog 3, RBFOX3)

Product Synonym Names
Anti -Fox3 (Fox-3, Fox-1 Homolog C, Hexaribonucleotide-binding Protein 3, Hrnbp3, Neuronal Nuclei, NeuN, RNA Binding Protein Fox-1 Homolog 3, RBFOX3)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for H8X6E5
Clonality
Polyclonal
Isotype
IgY
Host
Chicken
Species Reactivity
Human, Mouse
Specificity
Recognizes FOX3. Species Crossreactivity: human and mouse.
Purity/Purification
Affinity Purified
Affinity Purified
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Immunogen
Synthetic peptide corresponding to the Fox-3 gene product, shared between the human (NP_001076044) and mouse (NP_001020102) sequences, conjugated to KLH.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-Fox3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Fox3 antibody
Fox3 is one of a family of 3 mammalian Fox homologues. Fox was discovered in C. elegans as a gene involved in sex determination, and the name Fox is an acronym of "Feminizing locus on X". The Fox protein and its 3 mammalian homologues are all about 46kD proteins each of which includes a central highly conserved RRM type RNA recognition motif, which corresponds to a small ~70aa structure consisting of 4 beta strands and two alpha-helices. An alternate name for Fox 3 is hexaribonucleotide binding protein 3, and these proteins are believed to have a role in the regulation of mRNA splicing.

Much interest has focused on Fox3 as this protein corresponds to NeuN, a neuronal nuclear antigen. NeuN antibody has become very widely used as a robust marker of neurons and neuronal stem cells. Fox3 is therefore a protein which has a funciton in RNA splicing and is expressed heavily and specifically in neuronal nuclei.
Product Categories/Family for anti-Fox3 antibody
Applications Tested/Suitable for anti-Fox3 antibody
Immunohistochemistry (IHC), Immunocytochemistry (ICC)
Application Notes for anti-Fox3 antibody
Suitable for use in Immunohistochemistry and Immunocytochemistry.
Dilution: Immunohistochemistry: 1:1000
NCBI/Uniprot data below describe general gene information for Fox3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
UniProt Primary Accession #
Molecular Weight
42,833 Da[Similar Products]
NCBI Official Full Name
Fox3 peroxisomal 3-oxoacyl CoA thiolase
UniProt Protein Name
Fox3 peroxisomal 3-oxoacyl CoA thiolase
Protein Family
UniProt Entry Name
H8X6E5_CANO9
UniProt Comments for Fox3
Sequence similarities: Belongs to the thiolase family. RuleBase RU003557
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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