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anti-GABRR1 antibody :: Rabbit anti-Human, Mouse GABRR1 Polyclonal Antibody

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Catalog # MBS7043674
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

GABRR1, Polyclonal Antibody

Popular Item
Also Known As

GABRR1 Antibody

Product Synonym Names
Gamma-aminobutyric acid receptor subunit rho-1; GABA(A) receptor subunit rho-1; GABA(C) receptor; GABRR1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
462
OMIM
137161
3D Structure
ModBase 3D Structure for P24046
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Gamma-aminobutyric acid receptor subunit rho-1 protein (365-465AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22960 / sc-21336 / sc-31452 / sc-16879 / sc-21338 / sc-25707
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-GABRR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GABRR1 antibody
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission.
Applications Tested/Suitable for anti-GABRR1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-GABRR1 antibody
Western blot
All lanes: GABRR1 antibody at 1.25ug/ml+mouse eye tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 56,54,46 kDa
Observed band size: 56 kDa

anti-GABRR1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-GABRR1 antibody
Immunohistochemistry of paraffin-embedded human tonsil tissue using MBS7043674 at dilution 1:100
anti-GABRR1 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-GABRR1 antibody
Immunohistochemistry of paraffin-embedded human thymus using MBS7043674 at dilution 1:100
anti-GABRR1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for GABRR1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
45,516 Da
NCBI Official Full Name
gamma-aminobutyric acid receptor subunit rho-1 isoform b
NCBI Official Synonym Full Names
gamma-aminobutyric acid type A receptor rho1 subunit
NCBI Official Symbol
GABRR1  [Similar Products]
NCBI Protein Information
gamma-aminobutyric acid receptor subunit rho-1
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit rho-1
UniProt Synonym Protein Names
GABA(A) receptor subunit rho-1; GABA(C) receptor
UniProt Gene Name
GABRR1  [Similar Products]
UniProt Entry Name
GBRR1_HUMAN
NCBI Summary for GABRR1
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
UniProt Comments for GABRR1
GABRR1: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR1 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Membrane protein, integral; Receptor, misc.; Membrane protein, multi-pass; Channel, ligand-gated; Transporter, ion channel; Channel, chloride

Chromosomal Location of Human Ortholog: 6q15

Cellular Component: integral to plasma membrane; plasma membrane

Biological Process: gamma-aminobutyric acid signaling pathway; synaptic transmission; transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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