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anti-GRPEL2 antibody :: Rabbit anti-Human, Mouse GRPEL2 Polyclonal Antibody

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Catalog # MBS9128817
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.1 mL  /  $305 +1 FREE 8GB USB
  0.2 mL  /  $460 +1 FREE 8GB USB
Product Name

GRPEL2, Polyclonal Antibody

Popular Item
Full Product Name

GRPEL2 Polyclonal Antibody

Product Gene Name

anti-GRPEL2 antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Immunogen Sequence Positions
33-225
3D Structure
ModBase 3D Structure for Q8TAA5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Affinity Purification
Category
Primary antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 33-225 of human GRPEL2.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Notes
Small volumes of anti-GRPEL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Applications Tested/Suitable for anti-GRPEL2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-GRPEL2 antibody
WB: 1:500 - 1:2000
IHC: 1:50-1:100
Western Blot (WB) of anti-GRPEL2 antibody
Western blot analysis of extracts of various cell lines, using GRPEL2 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
anti-GRPEL2 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-GRPEL2 antibody
Immunohistochemistry of paraffin-embedded human esophagus using GRPEL2 antibody at dilution of 1:100 (40x lens).
anti-GRPEL2 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-GRPEL2 antibody
Immunohistochemistry of paraffin-embedded mouse brain using GRPEL2 antibody at dilution of 1:100 (40x lens).
anti-GRPEL2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for GRPEL2. It may not necessarily be applicable to this product.
NCBI GI #
40255109
NCBI GeneID
134266
NCBI Accession #
NP_689620.2 [Other Products]
NCBI GenBank Nucleotide #
NM_152407.3 [Other Products]
UniProt Primary Accession #
Q8TAA5 [Other Products]
UniProt Secondary Accession #
Q49AJ6; B4DFA6[Other Products]
UniProt Related Accession #
Q8TAA5[Other Products]
Molecular Weight
25kDa
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NCBI Official Full Name
grpE protein homolog 2, mitochondrial
NCBI Official Synonym Full Names
GrpE-like 2, mitochondrial (E. coli)
NCBI Official Symbol
GRPEL2  [Similar Products]
NCBI Official Synonym Symbols
Mt-GrpE#2
  [Similar Products]
NCBI Protein Information
grpE protein homolog 2, mitochondrial
UniProt Protein Name
GrpE protein homolog 2, mitochondrial
UniProt Synonym Protein Names
Mt-GrpE#2
Protein Family
GrpE protein
UniProt Gene Name
GRPEL2  [Similar Products]
UniProt Entry Name
GRPE2_HUMAN
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UniProt Comments for GRPEL2
GRPEL2: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70. Belongs to the GrpE family.

Chromosomal Location of Human Ortholog: 5q32

Cellular Component: mitochondrion; mitochondrial matrix; mitochondrial inner membrane

Molecular Function: protein homodimerization activity; adenyl-nucleotide exchange factor activity; chaperone binding; unfolded protein binding

Biological Process: cellular protein metabolic process; protein folding; regulation of catalytic activity; protein targeting to mitochondrion
Research Articles on GRPEL2
1. Observational study of gene-disease association. (HuGE Navigator)
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-GRPEL2 antibody
 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Mitochondrial Protein Import Pathway antibodies  Mitochondrial Protein Import Pathway Diagram
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