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anti-GSC2 antibody :: Rabbit anti-Human, Mouse GSC2 Polyclonal Antibody

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Catalog # MBS9604482
Unit / Price
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  0.1 mL  /  $255 +1 FREE 8GB USB
  0.2 mL  /  $295 +1 FREE 8GB USB
Product Name

GSC2, Polyclonal Antibody

Popular Item
Full Product Name

GSC2 Antibody

Product Synonym Names
GSC 2; GSCL; Homeobox protein goosecoid 2; Homeobox protein goosecoid like
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O15499
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Specificity
GSC2 antibody detects endogenous levels of total GSC2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human GSC2
Subcellular Location
Nuclear
Tissue Specificity
Detected in adult testis and pituitary, and in 9-10 week fetal tissue (thorax). Probably expressed in other tissues at low levels.
Predicted Cross Reactivity
Pig, Bovine, Chicken
Similarity
Pig (100%), Bovine (100%), Chicken (82%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-GSC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GSC2 antibody
Function: May have a role in development. May regulate its own transcription. May bind the bicoid consensus sequence TAATCC.
Similarity: Belongs to the paired homeobox family. Bicoid subfamily.
Applications Tested/Suitable for anti-GSC2 antibody
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
Application Notes for anti-GSC2 antibody
WB: 1:1000-3000
IF/ICC: 1:100-1:500

Western Blot (WB) of anti-GSC2 antibody
Western blot analysis GSC2 using HUVEC whole cell lysates
anti-GSC2 antibody Western Blot (WB) (WB) image
Immunofluorescene (IF) of anti-GSC2 antibody
MBS9604482 staining 293 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
anti-GSC2 antibody Immunofluorescene (IF) image
Immunofluorescence (IF) of anti-GSC2 antibody
MBS9604482 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
anti-GSC2 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for GSC2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 25 kD
Predicted: 22 kDa
NCBI Official Full Name
homeobox protein goosecoid-2
NCBI Official Synonym Full Names
goosecoid homeobox 2
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
homeobox protein goosecoid-2
UniProt Protein Name
Homeobox protein goosecoid-2
UniProt Synonym Protein Names
Homeobox protein goosecoid-like; GSC-L
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
GSCL; GSC-2; GSC-L  [Similar Products]
NCBI Summary for GSC2
Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development. [provided by RefSeq, Jul 2008]
UniProt Comments for GSC2
May have a role in development. May regulate its own transcription. May bind the bicoid consensus sequence TAATCC.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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