• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-IL31 antibody :: Rabbit anti-Human, Mouse IL31 Polyclonal Antibody

Scan QR to view Datasheet
Catalog # MBS240345
Unit / Price
  0.05 mg  /  $530 +1 FREE 8GB USB
Product Name

IL31, Polyclonal Antibody

Also Known As

Rabbit Polyclonal to Human IL31

Product Synonym Names
Anti-IL31 Antibody (Internal) IHC-plus; IL31; IL-31; Interleukin 31; Interleukin-31; Human IL31
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
164
OMIM
609509
3D Structure
ModBase 3D Structure for Q6EBC2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Specificity
18 amino acid peptide from near the center of human IL-31
Purity/Purification
Affinity Purified
Form/Format
PBS, 0.02% sodium azide.
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic peptide from human IL31 / IL-31.
Immunogen Type
Synthetic peptide
Immunogen
IL31 antibody was raised against synthetic peptide from human IL31 / IL-31.
Antigen Modification
Internal
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Other Notes
Small volumes of anti-IL31 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-IL31 antibody
Applications Tested/Suitable for anti-IL31 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-IL31 antibody
IHC-P (5 ug/ml), WB
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...

Immunohistochemistry (IHC) of anti-IL31 antibody
Anti-IL-31 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
anti-IL31 antibody Immunohistochemistry (IHC) (IHC) image
Immunofluorescence (IF) of anti-IL31 antibody
Immunofluorescence of IL-31 in Human Skeletal Muscle cells with IL-31 antibody at 20 ug/ml.
anti-IL31 antibody Immunofluorescence (IF) image
Western Blot (WB) of anti-IL31 antibody
Western blot of IL-31 in human skeletal muscle tissue lysate with IL-31 antibody at (A) 2.5, (B) 5 and (C) 10 ug/ml.
anti-IL31 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for IL31. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
18,205 Da
NCBI Official Full Name
interleukin-31
NCBI Official Synonym Full Names
interleukin 31
NCBI Official Symbol
NCBI Official Synonym Symbols
IL-31
  [Similar Products]
NCBI Protein Information
interleukin-31
UniProt Protein Name
Interleukin-31
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
IL-31  [Similar Products]
UniProt Entry Name
IL31_HUMAN
NCBI Summary for IL31
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]
UniProt Comments for IL31
IL31: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.

Protein type: Cytokine; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: extracellular space

Molecular Function: cytokine activity

Biological Process: immune system process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000