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anti-ITGA9 antibody :: Goat anti-Human, Mouse Integrin, alpha9 Polyclonal Antibody

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Catalog # MBS611310
Unit / Price
  0.1 mg  /  $765 +1 FREE 8GB USB
anti-ITGA9 antibody
Product Name

Integrin, alpha9 (ITGA9), Polyclonal Antibody

Also Known As

Integrin, alpha9 (Integrin alpha4-like)

Product Synonym Names
Anti -Integrin, alpha9 (Integrin alpha4-like)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 3; NC_000003.11 (37493813..37861281). Location: 3p21.3
OMIM
603963
3D Structure
ModBase 3D Structure for Q13797
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Human, Mouse
Specificity
Recognizes mouse Integrin alpha9. Shows <5% crossreactivity with recombinant human Integrin alpha1, alpha8, alpha9, alphaL, recombinant mouse Integrin 3, 4, 5, E and M.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 500ul sterile PBS.
Immunogen
Recombinant protein corresponding to Try31-Val979 from mouse Integin alpha9 expressed in NSO cells (NP_598482).
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
Other Notes
Small volumes of anti-ITGA9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ITGA9 antibody
Integrin alpha9 is a 150kD type I transmembrane glycoprotein that is widely expressed and is found on smooth muscle, keratinocytes, skeletal muscle and hepatocytes. It principally associates with the beta1 integrin. Alpha9beta1 binds to VEGF-C and D, and osteopontin. The 951 amino acid (aa) extracellular domain of mouse integrin alpha9 contains three beta-propellor repeats and multiple PheGly-GlyAlaPro repeats. A potential proteolytic cleavage site in human alpha9 ECD is absolutely conserved in mouse alpha9 ECD (Arg 566-Val 567). The ECD of mouse integrin alpha9 shares 95% and 89% aa sequence identity to rat and human integrin alpha9, respectively.
Product Categories/Family for anti-ITGA9 antibody
Applications Tested/Suitable for anti-ITGA9 antibody
ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes for anti-ITGA9 antibody
Suitable for use in Western Blot, Flow Cytometry and ELISA.
Dilution: Western Blot: 0.1ug/ml. Tested on recombinant mouse Integrin alpha9.
Flow Cytometry: 2.5ug labels 10e6 cells. Tested on D3 mouse embryonic stem cells.
Optimal dilutions should be determined by each laboratory for each application.
NCBI/Uniprot data below describe general gene information for ITGA9. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
114,489 Da[Similar Products]
NCBI Official Full Name
integrin alpha-9
NCBI Official Synonym Full Names
integrin, alpha 9
NCBI Official Symbol
ITGA9  [Similar Products]
NCBI Official Synonym Symbols
RLC; ITGA4L; ALPHA-RLC
  [Similar Products]
NCBI Protein Information
integrin alpha-9; OTTHUMP00000161385; integrin alpha-RLC
UniProt Protein Name
Integrin alpha-9
UniProt Synonym Protein Names
Integrin alpha-RLC
Protein Family
UniProt Gene Name
ITGA9  [Similar Products]
UniProt Entry Name
ITA9_HUMAN
NCBI Summary for ITGA9
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq]
UniProt Comments for ITGA9
ITGA9: Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G- I-E-L in cytotactin. Belongs to the integrin alpha chain family.

Protein type: Cell adhesion; Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: plasma membrane; basal plasma membrane; integrin complex

Molecular Function: collagen binding; metal ion binding; laminin binding

Biological Process: integrin-mediated signaling pathway; axon guidance; neutrophil chemotaxis; extracellular matrix organization and biogenesis; wound healing; cell adhesion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-ITGA9 antibody
 Reference Product  PubMed Publications
 ITGB1 antibody  >3 publications with ITGA9 and ITGB1
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