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anti-MNDA antibody :: Rabbit anti-Human, Mouse MNDA Polyclonal Antibody

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Catalog # MBS7052153
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

MNDA, Polyclonal Antibody

Popular Item
Also Known As

MNDA Antibody

Product Synonym Names
Myeloid cell nuclear differentiation antigen; MNDA
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
407
OMIM
M81750 mRNA
3D Structure
ModBase 3D Structure for P41218
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Immunogen
Recombinant Human Myeloid cell nuclear differentiation antigen protein (84-233AA)
Conjugation
Non-conjugated
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-MNDA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MNDA antibody
May act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1.
Applications Tested/Suitable for anti-MNDA antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-MNDA antibody
WB: 1:500-1:5000
IHC: 1:20-1:200
IF: 1:50-1:200

Western Blot (WB) of anti-MNDA antibody
Western Blot
Positive WB detected in: Mouse heart tissue,Mouse kidney tissue
All lanes: MNDA antibody at 4ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 46 KDa
Observed band size: 46 KDa

anti-MNDA antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-MNDA antibody
Immunohistochemistry of paraffin-embedded human skin tissue using MBS7052153 at dilution of 1:100
anti-MNDA antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-MNDA antibody
Immunofluorescent analysis of MCF-7 cells using MBS7052153 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-MNDA antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for MNDA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
45,836 Da
NCBI Official Full Name
myeloid cell nuclear differentiation antigen
NCBI Official Synonym Full Names
myeloid cell nuclear differentiation antigen
NCBI Official Symbol
NCBI Official Synonym Symbols
PYHIN3
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NCBI Protein Information
myeloid cell nuclear differentiation antigen
UniProt Protein Name
Myeloid cell nuclear differentiation antigen
UniProt Gene Name
NCBI Summary for MNDA
The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq, Jul 2008]
UniProt Comments for MNDA
May act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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