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anti-MYO3A antibody :: Rabbit anti-Human, Mouse MYO3A Polyclonal Antibody

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Catalog # MBS8530231
Unit / Price
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  0.1 mg  /  $290 +1 FREE 8GB USB
anti-MYO3A antibody
Product Name

MYO3A, Polyclonal Antibody

Popular Item
Full Product Name

MYO3A Polyclonal Antibody

Product Synonym Names
Myosin-IIIa; EC 2.7.11.1; MYO3A
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
606808
3D Structure
ModBase 3D Structure for Q8NEV4
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Immunogen
Synthesized peptide derived from human protein. at AA range: 180-260
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-MYO3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-MYO3A antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-MYO3A antibody
WB: 1:500-2000
ELISA: 1:5000-20000
NCBI/Uniprot data below describe general gene information for MYO3A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
177
NCBI Official Full Name
myosin-IIIa
NCBI Official Synonym Full Names
myosin IIIA
NCBI Official Symbol
MYO3A  [Similar Products]
NCBI Official Synonym Symbols
DFNB30
  [Similar Products]
NCBI Protein Information
myosin-IIIa
UniProt Protein Name
Myosin-IIIa
Protein Family
UniProt Gene Name
MYO3A  [Similar Products]
NCBI Summary for MYO3A
The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea. [provided by RefSeq, Jul 2008]
UniProt Comments for MYO3A
Probable actin-based motor with a protein kinase activity. Probably plays a role in vision and hearing (PubMed:12032315). Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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