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anti-NOSTRIN antibody :: Rabbit anti-Human, mouse NOSTRIN Polyclonal Antibody

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Catalog # MBS7002625
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

NOSTRIN, Polyclonal Antibody

Popular Item
Also Known As

NOSTRIN Antibody

Product Synonym Names
Nostrin; NOSTRIN; BM247 homolog; Nitric oxide synthase traffic inducer; Nitric oxide synthase trafficker; eNOS-trafficking inducer
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
506
OMIM
607496
3D Structure
ModBase 3D Structure for Q8IVI9
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, mouse
Purity/Purification
Affinity Purified
Form/Format
Liquid
Immunogen
Recombinant human Nostrin protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-51345 / sc-51347 / sc-134803
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-NOSTRIN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-NOSTRIN antibody
Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.
Applications Tested/Suitable for anti-NOSTRIN antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-NOSTRIN antibody
Recommended dilution: WB:1:500-2000, IHC:1:20-1:200

Western Blot (WB) of anti-NOSTRIN antibody
Western blot
All lanes: NOSTRIN antibody at 6ug/ml
Lane 1: Mouse heart tissue
Lane 2: Mouse brain tissue
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 58,55,49,65 kDa
Observed band size: 58 kDa

anti-NOSTRIN antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-NOSTRIN antibody
Immunohistochemistry of paraffin-embedded human placenta tissue using MBS7002625 at dilution of 1:100
anti-NOSTRIN antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-NOSTRIN antibody
Immunohistochemistry of paraffin-embedded human heart tissue using MBS7002625 at dilution of 1:100
anti-NOSTRIN antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for NOSTRIN. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
64,364 Da
NCBI Official Full Name
nostrin isoform 2
NCBI Official Synonym Full Names
nitric oxide synthase trafficking
NCBI Official Symbol
NOSTRIN  [Similar Products]
NCBI Official Synonym Symbols
DaIP2
  [Similar Products]
NCBI Protein Information
nostrin
UniProt Protein Name
Nostrin
UniProt Synonym Protein Names
BM247 homolog; Nitric oxide synthase traffic inducer; Nitric oxide synthase trafficker; eNOS-trafficking inducer
Protein Family
UniProt Gene Name
NOSTRIN  [Similar Products]
UniProt Entry Name
NOSTN_HUMAN
NCBI Summary for NOSTRIN
Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 2004]
UniProt Comments for NOSTRIN
NOSTRIN: Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 2q31.1

Cellular Component: cytoskeleton; nucleus; plasma membrane

Molecular Function: DNA binding; protein binding

Biological Process: endocytosis; negative regulation of transcription, DNA-dependent; nitric oxide metabolic process; regulation of nitric-oxide synthase activity; signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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