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anti-NR2E1 antibody :: Rabbit anti-Human, Mouse NR2E1 Polyclonal Antibody

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Catalog # MBS7046707
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

NR2E1, Polyclonal Antibody

Popular Item
Also Known As

NR2E1 Antibody

Product Synonym Names
Nuclear receptor subfamily 2 group E member 1; Nuclear receptor TLX; Protein tailless homolog; Tll; hTll; NR2E1; TLX
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
422
OMIM
603849
3D Structure
ModBase 3D Structure for Q9Y466
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Nuclear receptor subfamily 2 group E member 1 protein (C-280AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-79573 / sc-133843 / sc-292096
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-NR2E1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-NR2E1 antibody
Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity). May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity). May be involved in retinoic acid receptor (RAR) regulation in retinal cells.
Applications Tested/Suitable for anti-NR2E1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-NR2E1 antibody
Western blot
All lanes: NR2E1antibody at 3.2ug/ml+ Mouse brain tissue
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 43,47 kDa
Observed band size: 43 kDa

anti-NR2E1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-NR2E1 antibody
Immunohistochemistry of paraffin-embedded human skin tissue using MBS7046707 at dilution 1:100
anti-NR2E1 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-NR2E1 antibody
Immunohistochemistry of paraffin-embedded human testis tissue using MBS7046707 at dilution 1:100
anti-NR2E1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for NR2E1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
46,400 Da
NCBI Official Full Name
nuclear receptor subfamily 2 group E member 1 isoform a
NCBI Official Synonym Full Names
nuclear receptor subfamily 2 group E member 1
NCBI Official Symbol
NR2E1  [Similar Products]
NCBI Official Synonym Symbols
TLL; TLX; XTLL
  [Similar Products]
NCBI Protein Information
nuclear receptor subfamily 2 group E member 1
UniProt Protein Name
Nuclear receptor subfamily 2 group E member 1
UniProt Synonym Protein Names
Nuclear receptor TLX; Protein tailless homolog; Tll; hTll
UniProt Gene Name
NR2E1  [Similar Products]
UniProt Synonym Gene Names
TLX; Tll; hTll  [Similar Products]
UniProt Entry Name
NR2E1_HUMAN
NCBI Summary for NR2E1
The protein encoded by this gene is an orphan receptor involved in retinal development. The encoded protein also regulates adult neural stem cell proliferation and may be involved in control of aggressive behavior. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
UniProt Comments for NR2E1
NR2E1: Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half- site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity. May be involved in retinoic acic receptor (RAR) regulation in retinal cells. Belongs to the nuclear hormone receptor family. NR2 subfamily.

Protein type: Nuclear receptor; DNA-binding

Chromosomal Location of Human Ortholog: 6q21

Cellular Component: nucleoplasm

Biological Process: nervous system development; transcription initiation from RNA polymerase II promoter
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-NR2E1 antibody
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