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anti-PDXK antibody :: Rabbit anti-Human, Mouse PDXK Polyclonal Antibody

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Catalog # MBS7043630
Unit / Price
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  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

PDXK, Polyclonal Antibody

Popular Item
Full Product Name

PDXK Antibody

Product Synonym Names
Pyridoxal kinase; Pyridoxine kinase; PDXK; C21orf124; C21orf97; PKH; PNK; PRED79
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
179020
3D Structure
ModBase 3D Structure for O00764
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Pyridoxal kinase protein (1-312AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-50961 / sc-67361
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-PDXK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PDXK antibody
Required for synthesis of pyridoxal-5-phosphate from vitamin B6.
Applications Tested/Suitable for anti-PDXK antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-PDXK antibody
Western blot
All lanes: PDXK antibody at 5.63ug/ml
Lane 1:mouse liver tissue
Lane 2:Hela whole cell lysate
Lane 3:mouse kidney tissue
Lane 4:HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 36,32,27 kDa
Observed band size: 35 kDa

anti-PDXK antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-PDXK antibody
Immunohistochemistry of paraffin-embedded human breast cancer using MBS7043630 at dilution 1:100
anti-PDXK antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-PDXK antibody
Immunohistochemistry of paraffin-embedded human colon cancer using MBS7043630 at dilution 1:100
anti-PDXK antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for PDXK. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
26,827 Da
NCBI Official Full Name
pyridoxal kinase
NCBI Official Synonym Full Names
pyridoxal (pyridoxine, vitamin B6) kinase
NCBI Official Symbol
NCBI Official Synonym Symbols
PKH; PNK; PRED79; C21orf97; HEL-S-1a; C21orf124
  [Similar Products]
NCBI Protein Information
pyridoxal kinase
UniProt Protein Name
Pyridoxal kinase
UniProt Synonym Protein Names
Pyridoxine kinase
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
C21orf124; C21orf97; PKH; PNK  [Similar Products]
UniProt Entry Name
PDXK_HUMAN
NCBI Summary for PDXK
The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
UniProt Comments for PDXK
PDXK: Required for synthesis of pyridoxal-5-phosphate from vitamin B6. Belongs to the pyridoxine kinase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cofactor and Vitamin Metabolism - vitamin B6; Kinase, other; EC 2.7.1.35

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus

Molecular Function: ATP binding; lithium ion binding; magnesium ion binding; potassium ion binding; protein homodimerization activity; pyridoxal kinase activity; pyridoxal phosphate binding; sodium ion binding; zinc ion binding

Biological Process: cell proliferation; pyridoxal 5'-phosphate salvage; pyridoxal phosphate biosynthetic process; vitamin B6 metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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