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anti-PECAM-1 antibody :: Rabbit anti-Human, Mouse PECAM-1 / CD31 Polyclonal Antibody

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Catalog # MBS242708
Unit / Price
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  0.05 mL  /  $530 +1 FREE 8GB USB
Product Name

PECAM-1 / CD31, Polyclonal Antibody

Popular Item
Full Product Name

Rabbit Polyclonal (IgG) to Human PECAM-1 / CD31

Product Synonym Names
Anti-PECAM-1 / CD31 Antibody (aa686-735) IHC-plus; PECAM1; CD31; CD31 antigen; EndoCAM; PECA1; PECAM-1; GPIIA; Human PECAM-1; CD31
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
173445
3D Structure
ModBase 3D Structure for P16284
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Specificity
PECAM-1 Antibody detects endogenous levels of total PECAM-1 protein.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic peptide from human PECAM-1 (aa686-735).
Immunogen
PECAM-1 / CD31 antibody was raised against synthetic peptide from human PECAM-1 (aa686-735).
Antigen Modification
aa686-735
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Other Notes
Small volumes of anti-PECAM-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PECAM-1 antibody
CD31 (PECAM1) is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. CD31 is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.
Applications Tested/Suitable for anti-PECAM-1 antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes for anti-PECAM-1 antibody
ELISA (1:20000), IF (1:100 - 1:500), IHC-P (10 ug/ml), WB (1:500 - 1:1000)

Immunohistochemistry (IHC) of anti-PECAM-1 antibody
Anti-CD31 antibody IHC of human tonsil, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-PECAM-1 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-PECAM-1 antibody
Anti-CD31 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-PECAM-1 antibody Immunohistochemistry (IHC) (IHC) image
Immunofluorescence (IF) of anti-PECAM-1 antibody
Immunofluorescence of HeLa cells, using PECAM-1 Antibody. The picture on the right is treated with the synthesized peptide.
anti-PECAM-1 antibody Immunofluorescence (IF) image
Western Blot (WB) of anti-PECAM-1 antibody
Western blot of extracts from Jurkat cells, using PECAM-1 Antibody. The lane on the right is treated with the synthesized peptide.
anti-PECAM-1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for PECAM-1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
81,378 Da
NCBI Official Full Name
platelet endothelial cell adhesion molecule
NCBI Official Synonym Full Names
platelet/endothelial cell adhesion molecule 1
NCBI Official Symbol
PECAM1  [Similar Products]
NCBI Official Synonym Symbols
CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM
  [Similar Products]
NCBI Protein Information
platelet endothelial cell adhesion molecule; CD31 antigen
UniProt Protein Name
Platelet endothelial cell adhesion molecule
UniProt Synonym Protein Names
EndoCAM; GPIIA'; PECA1; CD_antigen: CD31
UniProt Gene Name
PECAM1  [Similar Products]
UniProt Synonym Gene Names
PECAM-1  [Similar Products]
UniProt Entry Name
PECA1_HUMAN
NCBI Summary for PECAM-1
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]
UniProt Comments for PECAM-1
PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 17q23.3

Cellular Component: extracellular space; platelet alpha granule membrane; integral to membrane; plasma membrane; cell junction

Molecular Function: protein binding

Biological Process: platelet activation; extracellular matrix organization and biogenesis; platelet degranulation; diapedesis; cell recognition; signal transduction; blood coagulation; cell adhesion; leukocyte migration; phagocytosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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