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anti-PIK3R3 antibody :: Rabbit anti-Human, Mouse PIK3R3 Polyclonal Antibody

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Catalog # MBS7046379
Unit / Price
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  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

PIK3R3, Polyclonal Antibody

Popular Item
Full Product Name

PIK3R3 Antibody

Product Synonym Names
Phosphatidylinositol 3-kinase regulatory subunit gamma; PI3-kinase regulatory subunit gamma; PI3K regulatory subunit gamma; PtdIns-3-kinase regulatory subunit gamma; Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; PI3-kinase subunit p55-gamma; PtdIns-3-kinase regulatory subunit p55-gamma; p55PIK; PIK3R3
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
606076
3D Structure
ModBase 3D Structure for Q92569
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Phosphatidylinositol 3-kinase regulatory subunit gamma protein (N-230AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-48644
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-PIK3R3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PIK3R3 antibody
Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1.
Applications Tested/Suitable for anti-PIK3R3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-PIK3R3 antibody
Western blot
All lanes: PIK3R3 antibody at 3.5ug/ml
Lane 1: MCF7 whole cell lysate
Lane 2: Jurkat whole cell lysate
Lane 3: Mouse gonadal tissue
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 55,48,44 kDa
Observed band size: 54 kDa

anti-PIK3R3 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-PIK3R3 antibody
Immunohistochemistry of paraffin-embedded human testis tissue using MBS7046379 at dilution 1:100
anti-PIK3R3 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-PIK3R3 antibody
Immunohistochemistry of paraffin-embedded human brain tissue using MBS7046379 at dilution 1:100
anti-PIK3R3 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for PIK3R3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
43,465 Da
NCBI Official Full Name
phosphatidylinositol 3-kinase regulatory subunit gamma isoform 1
NCBI Official Synonym Full Names
phosphoinositide-3-kinase regulatory subunit 3
NCBI Official Symbol
PIK3R3  [Similar Products]
NCBI Official Synonym Symbols
p55; p55PIK; p55-GAMMA
  [Similar Products]
NCBI Protein Information
phosphatidylinositol 3-kinase regulatory subunit gamma
UniProt Protein Name
Phosphatidylinositol 3-kinase regulatory subunit gamma
UniProt Synonym Protein Names
Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; PI3-kinase subunit p55-gamma; PtdIns-3-kinase regulatory subunit p55-gamma; p55PIK
UniProt Gene Name
PIK3R3  [Similar Products]
UniProt Synonym Gene Names
PI3-kinase regulatory subunit gamma; PI3K regulatory subunit gamma; PtdIns-3-kinase regulatory subunit gamma; PI3-kinase subunit p55-gamma; PtdIns-3-kinase regulatory subunit p55-gamma  [Similar Products]
UniProt Entry Name
P55G_HUMAN
NCBI Summary for PIK3R3
Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity. [provided by RefSeq, Jun 2016]
UniProt Comments for PIK3R3
PIK3R3: Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. Heterodimer of a regulatory subunit PIK3R3 and a p110 catalytic subunit (PIK3CA, PIK3CB or PIK3CD). Interacts with AXL. Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle. Belongs to the PI3K p85 subunit family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Kinase, lipid; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1p34.1

Cellular Component: cytosol; phosphoinositide 3-kinase complex

Molecular Function: 1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-3-kinase regulator activity; protein binding

Biological Process: phosphatidylinositol biosynthetic process; regulation of phosphoinositide 3-kinase activity
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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