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anti-PMM1 antibody :: Rabbit anti-Human, mouse PMM1 Polyclonal Antibody

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Catalog # MBS7001010
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

PMM1, Polyclonal Antibody

Popular Item
Also Known As

PMM1 Antibody

Product Synonym Names
Phosphomannomutase 1; PMM 1; PMMH-22; PMM1; PMMH22
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
262
OMIM
601786
3D Structure
ModBase 3D Structure for Q92871
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, mouse
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Liquid
Immunogen
Recombinant human Phosphomannomutase 1 protrin(2-262aa)
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-86200 / sc-86201
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-PMM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PMM1 antibody
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain.
Applications Tested/Suitable for anti-PMM1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PMM1 antibody
Recommended dilution: WB:1:500-2000, IHC:1:20-1:200

Western Blot (WB) of anti-PMM1 antibody
Western blot
All lanes: PMM1 antibody at 2ug/ml
Lane 1:HepG2 whole cell lysate
Lane 2:NIH3T3 whole cell lysate
Lane 3:293T whole cell lysate
Lane 4:mouse brain tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 30kDa
Observed band size: 30kDa

anti-PMM1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-PMM1 antibody
Immunohistochemistry of paraffin-embedded human pancreas tissue using MBS7001010 at dilution 1:100
anti-PMM1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for PMM1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
29,747 Da
NCBI Official Full Name
phosphomannomutase 1
NCBI Official Synonym Full Names
phosphomannomutase 1
NCBI Official Symbol
NCBI Official Synonym Symbols
Sec53
  [Similar Products]
NCBI Protein Information
phosphomannomutase 1
UniProt Protein Name
Phosphomannomutase 1
UniProt Synonym Protein Names
PMMH-22
UniProt Gene Name
UniProt Synonym Gene Names
PMMH22; PMM 1  [Similar Products]
UniProt Entry Name
PMM1_HUMAN
NCBI Summary for PMM1
Phosphomannomutase catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. [provided by RefSeq, Jul 2008]
UniProt Comments for PMM1
PMM1: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain. Belongs to the eukaryotic PMM family.

Protein type: Carbohydrate Metabolism - fructose and mannose; EC 5.4.2.8; Isomerase; Carbohydrate Metabolism - amino sugar and nucleotide sugar

Chromosomal Location of Human Ortholog: 22q13.2

Cellular Component: cell soma; cytosol

Molecular Function: metal ion binding; phosphomannomutase activity; protein binding

Biological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; GDP-mannose biosynthetic process; mannose metabolic process; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withanti-PMM1 antibody
 Reference Product  PubMed Publications
 UBC antibody  >1 publications with PMM1 and UBC
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