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anti-PNMT antibody :: Rabbit anti-Human, Mouse PNMT Polyclonal Antibody

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Catalog # MBS9125654 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
Scan QR to view Datasheet
  0.05 mL  /  $200 +1 FREE 8GB USB
  0.1 mL  /  $275 +1 FREE 8GB USB
  0.2 mL  /  $430 +1 FREE 8GB USB
Western Blot (WB)
Product Name

PNMT, Polyclonal Antibody

Popular Item
Full Product Name

PNMT Polyclonal Antibody

Product Synonym Names
PENT; PNMTase
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
171190
3D Structure
ModBase 3D Structure for P11086
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Species
Human
Immunogen
Recombinant Protein
Immunogen
Recombinant protein of human PNMT
Calculated Molecular Weight
30kDa
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Notes
Small volumes of anti-PNMT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PNMT antibody
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.
Product Categories/Family for anti-PNMT antibody
Applications Tested/Suitable for anti-PNMT antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PNMT antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Western Blot (WB) of anti-PNMT antibody
Western blot analysis of extracts of various cell lines, using PNMT antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
anti-PNMT antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for PNMT. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
282
NCBI Official Full Name
Phenylethanolamine N-methyltransferase
NCBI Official Synonym Full Names
phenylethanolamine N-methyltransferase
NCBI Official Symbol
NCBI Official Synonym Symbols
PENT; PNMTase
  [Similar Products]
NCBI Protein Information
phenylethanolamine N-methyltransferase; phenylethanolamine N-methylase; noradrenaline N-methyltransferase
UniProt Protein Name
Phenylethanolamine N-methyltransferase
UniProt Synonym Protein Names
Noradrenaline N-methyltransferase
UniProt Gene Name
UniProt Synonym Gene Names
PENT; PNMTase  [Similar Products]
UniProt Entry Name
PNMT_HUMAN
NCBI Summary for PNMT
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]
UniProt Comments for PNMT
PNMT: Converts noradrenaline to adrenaline. Belongs to the NNMT/PNMT/TEMT family.

Protein type: Methyltransferase; EC 2.1.1.28; Amino Acid Metabolism - tyrosine

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: cytosol

Molecular Function: phenylethanolamine N-methyltransferase activity

Biological Process: methylation; catecholamine biosynthetic process; epinephrine biosynthetic process

Disease: Hypertension, Essential
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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