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anti-POU4F3 antibody :: Rabbit anti-Human, Mouse POU4F3 Polyclonal Antibody

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Catalog # MBS7045123
Unit / Price
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  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

POU4F3, Polyclonal Antibody

Popular Item
Full Product Name

POU4F3 Antibody

Product Synonym Names
POU domain; class 4; transcription factor 3; Brain-specific homeobox/POU domain protein 3C; Brain-3C; Brn-3C; POU4F3; BRN3C
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
602459
3D Structure
ModBase 3D Structure for Q15319
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human POU domain, class 4, transcription factor 3 protein (N-180AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-POU4F3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-POU4F3 antibody
May play a role in determining or maintaining the identities of a small subset of visual system neurons.
Applications Tested/Suitable for anti-POU4F3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-POU4F3 antibody
Western blot
All lanes: POU4F3antibody at 1.97ug/ml+ Mouse brain tissue
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 37 kDa
Observed band size: 37 kDa

anti-POU4F3 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-POU4F3 antibody
Immunohistochemistry of paraffin-embedded human brain tissue using MBS7045123 at dilution 1:100
anti-POU4F3 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-POU4F3 antibody
Immunohistochemistry of paraffin-embedded human placenta tissue using MBS7045123 at dilution 1:100
anti-POU4F3 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for POU4F3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,052 Da
NCBI Official Full Name
POU domain, class 4, transcription factor 3
NCBI Official Synonym Full Names
POU class 4 homeobox 3
NCBI Official Symbol
POU4F3  [Similar Products]
NCBI Official Synonym Symbols
BRN3C; DFNA15
  [Similar Products]
NCBI Protein Information
POU domain, class 4, transcription factor 3
UniProt Protein Name
POU domain, class 4, transcription factor 3
UniProt Synonym Protein Names
Brain-specific homeobox/POU domain protein 3C; Brain-3C; Brn-3C
UniProt Gene Name
POU4F3  [Similar Products]
UniProt Synonym Gene Names
BRN3C; Brain-3C; Brn-3C  [Similar Products]
UniProt Entry Name
PO4F3_HUMAN
NCBI Summary for POU4F3
This gene encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15. [provided by RefSeq, Mar 2009]
UniProt Comments for POU4F3
POU4F3: May play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in POU4F3 are the cause of deafness autosomal dominant type 15 (DFNA15). DFNA15 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Belongs to the POU transcription factor family. Class- 4 subfamily.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 5q32

Cellular Component: nucleoplasm

Molecular Function: transcription factor activity

Biological Process: positive regulation of transcription from RNA polymerase II promoter; visual perception

Disease: Deafness, Autosomal Dominant 15
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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