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anti-PPP2R3C antibody :: Rabbit anti-Human, Mouse PPP2R3C Polyclonal Antibody

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Catalog # MBS7043685
Unit / Price
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  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

PPP2R3C, Polyclonal Antibody

Popular Item
Full Product Name

PPP2R3C Antibody

Product Synonym Names
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma; Protein phosphatase subunit G5PR; Rhabdomyosarcoma antigen MU-RMS-40.6A/6C; PPP2R3C; C14orf10; G5PR
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
615902
3D Structure
ModBase 3D Structure for Q969Q6
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma protein (N-160AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-PPP2R3C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PPP2R3C antibody
May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells.
Applications Tested/Suitable for anti-PPP2R3C antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-PPP2R3C antibody
Western blot
All lanes: PPP2R3C antibody at 3.76 ug/ml
Lane 1: Mouse stomach tissue
Lane 2: Mouse brain tissue
Lane 3: A431 whole cell lysate
Lane 4: Jurkat whole cell lysate
Lane 5: A549 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 54,40 kDa
Observed band size: 53,30 kDa

anti-PPP2R3C antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-PPP2R3C antibody
Immunohistochemistry of paraffin-embedded human brain tissue using MBS7043685 at dilution of 1:100
anti-PPP2R3C antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-PPP2R3C antibody
Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7043685 at dilution of 1:100
anti-PPP2R3C antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for PPP2R3C. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,806 Da
NCBI Official Full Name
serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform 2
NCBI Official Synonym Full Names
protein phosphatase 2 regulatory subunit B''gamma
NCBI Official Symbol
PPP2R3C  [Similar Products]
NCBI Official Synonym Symbols
G4-1; G5pr; C14orf10
  [Similar Products]
NCBI Protein Information
serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma
UniProt Protein Name
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma
UniProt Synonym Protein Names
Protein phosphatase subunit G5PR; Rhabdomyosarcoma antigen MU-RMS-40.6A/6C
UniProt Gene Name
PPP2R3C  [Similar Products]
UniProt Synonym Gene Names
C14orf10; G5PR  [Similar Products]
UniProt Entry Name
P2R3C_HUMAN
NCBI Summary for PPP2R3C
This gene encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
UniProt Comments for PPP2R3C
PPP2R3C: May regulate MCM3AP phosphorylation through phosphatase recruitment. May play a role in the activation-induced cell death of B-cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein phosphatase, regulatory subunit

Chromosomal Location of Human Ortholog: 14q13.2

Cellular Component: centrosome; spindle

Molecular Function: protein binding

Biological Process: B cell homeostasis; cortical cytoskeleton organization and biogenesis; microtubule cytoskeleton organization and biogenesis; positive regulation of B cell differentiation; T cell homeostasis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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