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anti-PSCA antibody :: Rabbit anti-Human, Mouse PSCA Polyclonal Antibody

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Catalog # MBS2539386
Unit / Price
  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Western Blot (WB)
Product Name

PSCA, Polyclonal Antibody

Popular Item
Also Known As

PSCA Polyclonal Antibody

Product Synonym Names
PSCA; Prostate stem cell antigen
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS2539386 Technical Datasheet
OMIM
602470
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Affinity purification
Immunogen
Synthesized peptide derived from the Internal region of human PSCA.
Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-14201 / sc-14202
Calculated MW
13kDa
Observed MW
29kDa
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-PSCA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PSCA antibody
PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
Product Categories/Family for anti-PSCA antibody
Applications Tested/Suitable for anti-PSCA antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-PSCA antibody
WB: 1:500-1:2000, ELISA: 1:5000-1:20000

Western Blot (WB) of anti-PSCA antibody
Western Blot analysis of various cells using PSCA Polyclonal Antibody at dilution of 1:1000.
anti-PSCA antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for PSCA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
prostate stem cell antigen preproprotein
NCBI Official Synonym Full Names
prostate stem cell antigen
NCBI Official Symbol
NCBI Official Synonym Symbols
PRO232
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NCBI Protein Information
prostate stem cell antigen
UniProt Protein Name
Prostate stem cell antigen
UniProt Gene Name
UniProt Entry Name
PSCA_HUMAN
NCBI Summary for PSCA
This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
UniProt Comments for PSCA
PSCA: May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 8q24.2

Cellular Component: plasma membrane
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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