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anti-PTGIR antibody :: Rabbit anti-Human, Mouse PTGIR Polyclonal Antibody

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Catalog # MBS127986
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.1 mL  /  $305 +1 FREE 8GB USB
  0.2 mL  /  $460 +1 FREE 8GB USB
Product Name

PTGIR, Polyclonal Antibody

Popular Item
Full Product Name

PTGIR Polyclonal Antibody

Product Synonym Names
IP; PRIPR
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
600022
3D Structure
ModBase 3D Structure for P43119
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Species
Human
Immunogen
Recombinant Protein
Immunogen
Recombinant protein of human PTGIR
Calculated Molecular Weight
40kDa
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Notes
Small volumes of anti-PTGIR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PTGIR antibody
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.
Product Categories/Family for anti-PTGIR antibody
Applications Tested/Suitable for anti-PTGIR antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PTGIR antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Western Blot (WB) of anti-PTGIR antibody
Western blot analysis of extracts of various cell lines, using PTGIR antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.
anti-PTGIR antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-PTGIR antibody
Immunohistochemistry of paraffin-embedded human thyroid cancer using PTGIR antibody at dilution of 1:200 (40x lens).
anti-PTGIR antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-PTGIR antibody
Immunohistochemistry of paraffin-embedded human colon carcinoma using PTGIR antibody at dilution of 1:200 (40x lens).
anti-PTGIR antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-PTGIR antibody
Immunohistochemistry of paraffin-embedded human stomach using PTGIR antibody at dilution of 1:200 (40x lens).
anti-PTGIR antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-PTGIR antibody
Immunohistochemistry of paraffin-embedded human gastric cancer using PTGIR antibody at dilution of 1:200 (40x lens).
anti-PTGIR antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for PTGIR. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
386
NCBI Official Full Name
Prostacyclin receptor
NCBI Official Synonym Full Names
prostaglandin I2 (prostacyclin) receptor (IP)
NCBI Official Symbol
PTGIR  [Similar Products]
NCBI Official Synonym Symbols
IP; PRIPR
  [Similar Products]
NCBI Protein Information
prostacyclin receptor; PGI receptor; PGI2 receptor; prostanoid IP receptor; prostaglandin I2 receptor
UniProt Protein Name
Prostacyclin receptor
UniProt Synonym Protein Names
Prostaglandin I2 receptor; PGI receptor; PGI2 receptor; Prostanoid IP receptor
Protein Family
UniProt Gene Name
PTGIR  [Similar Products]
UniProt Synonym Gene Names
PRIPR; PGI receptor; PGI2 receptor  [Similar Products]
UniProt Entry Name
PI2R_HUMAN
NCBI Summary for PTGIR
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008]
UniProt Comments for PTGIR
PTGIR: Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: integral to plasma membrane; plasma membrane; cytosol

Molecular Function: G-protein coupled receptor activity; guanyl-nucleotide exchange factor activity

Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; cell-cell signaling; negative regulation of smooth muscle cell proliferation; positive regulation of cAMP biosynthetic process; response to lipopolysaccharide; blood coagulation; G-protein signaling, adenylate cyclase activating pathway; positive regulation of GTPase activity
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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