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anti-ALDH1A1 antibody :: Rabbit anti-Human, Mouse Retinal dehydrogenase 1 Polyclonal Antibody

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Catalog # MBS1494169
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

Retinal dehydrogenase 1 (ALDH1A1), Polyclonal Antibody

Popular Item
Full Product Name

Rabbit anti-human Retinal dehydrogenase 1 polyclonal Antibody(ALDH1A1)

Product Synonym Names
RALDH 1; RalDH1; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase; cytosolic; ALDH1A1; ALDC; ALDH1; PUMB1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
100640
3D Structure
ModBase 3D Structure for P00352
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Retinal dehydrogenase 1 protein(202-501aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22588 / sc-22589 / sc-50385
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-ALDH1A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ALDH1A1 antibody
Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid
Applications Tested/Suitable for anti-ALDH1A1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ALDH1A1 antibody
Recommended dilution: WB:1:500-2000
IHC:1:20-1:200

Western Blot (WB) of anti-ALDH1A1 antibody
Western blot
All lanes: Retinal dehydrogenase 1 antibody at 4ug/ml+mouse liver tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 55kDa
Observed band size: 55kDa

anti-ALDH1A1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ALDH1A1 antibody
Immunohistochemistry of paraffin-embedded human small intestine using MBS1494169 at dilution 1:100
anti-ALDH1A1 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-ALDH1A1 antibody
Immunohistochemistry of paraffin-embedded human testicle using MBS1494169 at dilution 1:100
anti-ALDH1A1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ALDH1A1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,862 Da
NCBI Official Full Name
retinal dehydrogenase 1
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family member A1
NCBI Official Symbol
ALDH1A1  [Similar Products]
NCBI Official Synonym Symbols
ALDC; ALDH1; HEL-9; HEL12; PUMB1; ALDH11; RALDH1; ALDH-E1; HEL-S-53e
  [Similar Products]
NCBI Protein Information
retinal dehydrogenase 1
UniProt Protein Name
Retinal dehydrogenase 1
UniProt Synonym Protein Names
ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic
Protein Family
UniProt Gene Name
ALDH1A1  [Similar Products]
UniProt Synonym Gene Names
ALDC; ALDH1; PUMB1; RALDH 1; RalDH1  [Similar Products]
UniProt Entry Name
AL1A1_HUMAN
NCBI Summary for ALDH1A1
The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]
UniProt Comments for ALDH1A1
ALDH1A1: Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family.

Protein type: Cofactor and Vitamin Metabolism - retinol; Apoptosis; GAPs; Oxidoreductase; GAPs, Ras; EC 1.2.1.36

Chromosomal Location of Human Ortholog: 9q21.13

Cellular Component: cytoplasm; cytosol

Molecular Function: aldehyde dehydrogenase (NAD) activity; androgen binding; benzaldehyde dehydrogenase (NAD+) activity; GTPase activator activity; retinal dehydrogenase activity

Biological Process: aldehyde metabolic process; ethanol oxidation; positive regulation of GTPase activity; retinol metabolic process; xenobiotic metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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