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anti-SELP antibody :: Rabbit Selenoprotein P Polyclonal Antibody

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Catalog # MBS1489265
Unit / Price
  0.05 mg  /  $160 +1 FREE 8GB USB
  0.1 mg  /  $235 +1 FREE 8GB USB
Product Name

Selenoprotein P (SELP), Polyclonal Antibody

Popular Item
Also Known As

Rabbit anti-human Selenoprotein P polyclonal Antibody

Product Synonym Names
SEPP1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
381
OMIM
601484
3D Structure
ModBase 3D Structure for P49908
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse. Other species are not tested. Please decide the specificity by homology
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Selenoprotein P protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22639 / sc-22637 / sc-30162
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-SELP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-SELP antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-SELP antibody
Western blot
All lanes: Selenoprotein P antibody at 2ug/ml+mouse heart tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 43kDa
Observed band size: 43kDa

anti-SELP antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-SELP antibody
Immunohistochemistry of paraffin-embedded human kidney tissue using MBS1489265 at dilution 1:100
anti-SELP antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-SELP antibody
Immunohistochemistry of paraffin-embedded human thyroid tissue using MBS1489265 at dilution 1:100
anti-SELP antibody Immunohistochemistry (IHC) (IHC) image
Western Blot (WB) of anti-SELP antibody
Western Blot
Positive WB detected in: mouse brain,mouse skeletal muscle
All lanes: SEPP1 antibody at 4ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 43 kDa
Observed band size: 43,40 kDa

anti-SELP antibody Western Blot (WB) (WB) image
Immunofluorescence (IF) of anti-SELP antibody
Immunofluorescent analysis of HepG2 cells using MBS1489265 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-SELP antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for SELP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
43,174 Da
NCBI Official Full Name
selenoprotein P isoform 1
NCBI Official Synonym Full Names
selenoprotein P, plasma, 1
NCBI Official Symbol
SEPP1  [Similar Products]
NCBI Official Synonym Symbols
SeP; SELP; SEPP
  [Similar Products]
NCBI Protein Information
selenoprotein P
UniProt Protein Name
Selenoprotein P
Protein Family
UniProt Gene Name
SEPP1  [Similar Products]
UniProt Synonym Gene Names
SELP; SeP  [Similar Products]
UniProt Entry Name
SEPP1_HUMAN
NCBI Summary for SELP
This gene encodes a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues per polypeptide. It is a heparin-binding protein that appears to be associated with endothelial cells, and has been implicated to function as an antioxidant in the extracellular space. Several transcript variants, encoding either the same or different isoform, have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for SELP
SEPP1: Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis. Belongs to the selenoprotein P family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: extracellular region; extracellular space

Molecular Function: selenium binding

Biological Process: brain development; growth; locomotory behavior; post-embryonic development; response to oxidative stress; selenium metabolic process; sexual reproduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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