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anti-SLC22A8 antibody :: Rabbit anti-Human, Mouse SLC22A8 Polyclonal Antibody

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Catalog # MBS7044950
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

SLC22A8, Polyclonal Antibody

Popular Item
Also Known As

SLC22A8 Antibody

Product Synonym Names
Solute carrier family 22 member 8; Organic anion transporter 3; hOAT3; SLC22A8; OAT3
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
542
OMIM
607581
3D Structure
ModBase 3D Structure for Q8TCC7
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Solute carrier family 22 member 8 protein (C-70AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-107836
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-SLC22A8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SLC22A8 antibody
Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone-3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA).
Applications Tested/Suitable for anti-SLC22A8 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-SLC22A8 antibody
Western blot
All lanes: SLC22A8antibody IgG at 1.62ug/ml+ Mouse kidney tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 60,61,47,12,50 kDa
Observed band size: 60 kDa

anti-SLC22A8 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-SLC22A8 antibody
Immunohistochemistry of paraffin-embedded human kidney tissue MBS7044950 at dilution 1:100
anti-SLC22A8 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-SLC22A8 antibody
Immunohistochemistry of paraffin-embedded human adrenal gland tissue MBS7044950 at dilution 1:100
anti-SLC22A8 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for SLC22A8. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
49,821 Da
NCBI Official Full Name
solute carrier family 22 member 8 isoform 1
NCBI Official Synonym Full Names
solute carrier family 22 member 8
NCBI Official Symbol
SLC22A8  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
solute carrier family 22 member 8
UniProt Protein Name
Solute carrier family 22 member 8
UniProt Synonym Protein Names
Organic anion transporter 3; hOAT3
Protein Family
UniProt Gene Name
SLC22A8  [Similar Products]
UniProt Synonym Gene Names
OAT3; hOAT3  [Similar Products]
UniProt Entry Name
S22A8_HUMAN
NCBI Summary for SLC22A8
This gene encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, May 2010]
UniProt Comments for SLC22A8
SLC22A8: Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone- 3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA). Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC family

Chromosomal Location of Human Ortholog: 11q11

Cellular Component: basolateral plasma membrane; integral to plasma membrane; plasma membrane

Molecular Function: anion:anion antiporter activity; inorganic anion exchanger activity; sodium-independent organic anion transmembrane transporter activity

Biological Process: sodium-independent organic anion transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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