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anti-SNX18 antibody :: Rabbit anti-Human, Mouse SNX18 Polyclonal Antibody

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Catalog # MBS7046550
Unit / Price
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  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

SNX18, Polyclonal Antibody

Popular Item
Full Product Name

SNX18 Antibody

Product Synonym Names
Sorting nexin-18; SH3 and PX domain-containing protein 3B; Sorting nexin-associated Golgi protein 1; SNX18; SH3PXD3B; SNAG1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q96RF0
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Species
Human
Immunogen
Recombinant human Sorting nexin-18 protein (C-180AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-165518
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-SNX18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SNX18 antibody
Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.
Applications Tested/Suitable for anti-SNX18 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-SNX18 antibody
Western blot
All lanes: SNX18 antibody at 1.6ug/ml
Lane 1: A549 whole cell lysate
Lane 2: Hela whole cell lysate
Lane 3: Mouse kidney tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 69,70,65 kDa
Observed band size: 69 kDa

anti-SNX18 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-SNX18 antibody
Immunohistochemistry of paraffin-embedded human tonsil tissue MBS7046550 at dilution 1:100
anti-SNX18 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-SNX18 antibody
Immunohistochemistry of paraffin-embedded human small intestine MBS7046550 at dilution 1:100
anti-SNX18 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for SNX18. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
Molecular Weight
64,752 Da
NCBI Official Full Name
sorting nexin-18 isoform a
UniProt Protein Name
Sorting nexin-18
UniProt Synonym Protein Names
SH3 and PX domain-containing protein 3B; Sorting nexin-associated Golgi protein 1
Protein Family
UniProt Gene Name
SNX18  [Similar Products]
UniProt Synonym Gene Names
SH3PXD3B; SNAG1  [Similar Products]
UniProt Entry Name
SNX18_HUMAN
UniProt Comments for SNX18
SNX18: May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane. Belongs to the sorting nexin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 5q11.2

Cellular Component: clathrin-coated vesicle; cytoplasmic membrane-bound vesicle; endosome; extrinsic to internal side of plasma membrane; intracellular membrane-bound organelle; nucleoplasm

Molecular Function: phosphatidylinositol-4,5-bisphosphate binding; protein binding

Biological Process: cytokinesis after mitosis; endocytosis; endosome transport; positive regulation of GTPase activity; vesicle organization and biogenesis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-SNX18 antibody
Organs/Tissues associated with anti-SNX18 antibody
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