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anti-STIM1 antibody :: Rabbit stromal interaction molecule 1 Polyclonal Antibody

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Catalog # MBS710294
Unit / Price
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  0.05 mL  /  $230 +1 FREE 8GB USB
  0.15 mL  /  $500 +1 FREE 8GB USB
anti-STIM1 antibody
Product Name

stromal interaction molecule 1 (STIM1), Polyclonal Antibody

Popular Item
Full Product Name

Rabbit anti-human stromal interaction molecule 1 polyclonal Antibody

Product Synonym Names
stromal interaction molecule 1; STIM1; D11S4896E; GOK
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS710294 Technical Datasheet
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse; other species not tested. Please decide the specificity by homology.
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Immunogen
Human STIM1
Conjugate
Non-conjugated
Storage Buffer
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-79106 / sc-68897
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-STIM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-STIM1 antibody
Plays a role in mediating store-operated Ca2+ entry (SOCE), a Ca2+ influx following depletion of intracellular Ca2+ stores. Acts as Ca2+ sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca2+ depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca2+ release-activated Ca2+ (CRAC) channel subunit, TMEM142A/ORAI1.
Applications Tested/Suitable for anti-STIM1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-STIM1 antibody
ELISA: Use at an assay dependent dilution.
WB: 1:200-1:2000
IP: 1:500-1:5000
IHC: 1:20-1:200
IF: 1:10-1:100

Positive WB detected in: Jurkat cells, BxPC-3 cells, HT-1080 cells, mouse liver tissue, NIH/3T3 cells, Raji cells
Positive IP detected in: Raji cells
Positive IHC detected in: Human ovary tumor tissue, human lung cancer tissue
Positive IF detected in: HepG2 cells
NCBI/Uniprot data below describe general gene information for STIM1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Related Accession #
Molecular Weight
77,151 Da[Similar Products]
NCBI Official Full Name
stromal interaction molecule 1
NCBI Official Symbol
STIM1  [Similar Products]
NCBI Protein Information
stromal interaction molecule 1
UniProt Protein Name
Stromal interaction molecule 1
UniProt Gene Name
STIM1  [Similar Products]
UniProt Entry Name
STIM1_BOVIN
UniProt Comments for STIM1
Plays a role in mediating store-operated Ca2+ entry (SOCE), a Ca2+ influx following depletion of intracellular Ca2+ stores. Acts as Ca2+ sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca2+ depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca2+ release-activated Ca2+ (CRAC) channel subunit ORAI1. Involved in enamel formation. Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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