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anti-ENTPD3 antibody :: Rabbit anti-Human, Mouse T-cadherin Polyclonal Antibody

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Catalog # MBS150632
Unit / Price
  0.1 mg  /  $375 +1 FREE 8GB USB
Product Name

T-cadherin (ENTPD3), Polyclonal Antibody

Full Product Name

T-cadherin Antibody

Product Synonym Names
T-cadherin; HB6; CD39L3; NTPDase-3; Ectonucleoside triphosphate diphosphohydrolase 3; CD39 antigen-like 3; NTPDase 3; ectonucleoside triphosphate diphosphohydrolase 3
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
603161
3D Structure
ModBase 3D Structure for O75355
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Specificity
At least two isoforms of T-cadherin are known to exist.
Purity/Purification
T-cadherin Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (lot specific)
Conjugate
Unconjugated
Immunogen
T-cadherin antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human T-cadherin.
Buffer
T-cadherin Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
T-cadherin antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Other Notes
Small volumes of anti-ENTPD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ENTPD3 antibody
T-cadherin Antibody: T-cadherin was initially identified as cadherin-type cell adhesion molecule expressed in various neuronal populations in a temporally and spatially restricted pattern during axon growth. T-cadherin is an atypical member of the cadherin family because it does not possess the typical transmembrane and cytoplasmic domains but is instead anchored to the plasma membrane by glycosylphosphatidylinositol (GPI) linkage. T-cadherin may play a role in malignant tumor development as loss of the chromosome locus containing the T-cadherin gene correlates with the development of a variety of cancers. Recently it has been shown that T-cadherin can act as a receptor for hexameric and high-molecular weight forms of adiponectin, suggesting that T-cadherin may also play a role in metabolic regulation.
Applications Tested/Suitable for anti-ENTPD3 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-ENTPD3 antibody
T-cadherin antibody can be used for the detection of T-cadherin by Western blot at 0.5 - 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 20 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-ENTPD3 antibody
Western blot analysis of T-cadherin in 3T3 lysate with T-cadherin antibody at (A) 0.5 and (B) 1 μg/mL.
anti-ENTPD3 antibody Western Blot (WB) (WB) image
Immunofluorescence (IF) of anti-ENTPD3 antibody
Immunofluorescence of T-cadherin in K562 cells with T-cadherin antibody at 20 μg/mL.
anti-ENTPD3 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for ENTPD3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Predicted: 78; 84 kDa

Observed: 85 kDa
NCBI Official Full Name
Homo sapiens ectonucleoside triphosphate diphosphohydrolase 3 (ENTPD3), mRNA
NCBI Official Synonym Full Names
ectonucleoside triphosphate diphosphohydrolase 3
NCBI Official Symbol
ENTPD3  [Similar Products]
NCBI Official Synonym Symbols
HB6; CD39L3; NTPDase-3
  [Similar Products]
NCBI Protein Information
ectonucleoside triphosphate diphosphohydrolase 3; NTPDase 3; ecto-ATPase 3; ecto-ATPDase 3; ecto-apyrase 3; CD39 antigen-like 3; ecto-ATP diphosphohydrolase 3
UniProt Protein Name
Ectonucleoside triphosphate diphosphohydrolase 3
UniProt Synonym Protein Names
CD39 antigen-like 3; Ecto-ATP diphosphohydrolase 3; Ecto-ATPDase 3; Ecto-ATPase 3; Ecto-apyrase 3; HB6
UniProt Gene Name
ENTPD3  [Similar Products]
UniProt Synonym Gene Names
CD39L3; NTPDase 3; Ecto-ATPDase 3; Ecto-ATPase 3  [Similar Products]
UniProt Entry Name
ENTP3_HUMAN
NCBI Summary for ENTPD3
This gene encodes a plasma membrane-bound divalent cation-dependent E-type nucleotidase. The encoded protein is involved in the regulation of extracellular levels of ATP by hydrolysis of it and other nucleotides. Multiple transcript variants have been described. [provided by RefSeq, May 2014]
UniProt Comments for ENTPD3
ENTPD3: Has a threefold preference for the hydrolysis of ATP over ADP. Belongs to the GDA1/CD39 NTPase family.

Protein type: Membrane protein, integral; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Phosphatase (non-protein); Membrane protein, multi-pass; EC 3.6.1.5; Hydrolase

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: plasma membrane; integral to membrane

Molecular Function: nucleoside-diphosphatase activity; nucleoside-triphosphatase activity; ATP binding

Biological Process: nucleoside diphosphate catabolic process; nucleoside triphosphate catabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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