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anti-TNNC2 antibody :: Rabbit anti-Human, Mouse TNNC2 Polyclonal Antibody

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Catalog # MBS1496004
Unit / Price
  0.05 mL  /  $120 +1 FREE 8GB USB
  0.1 mL  /  $160 +1 FREE 8GB USB
Product Name

TNNC2, Polyclonal Antibody

Popular Item
Also Known As

Rabbit anti-human TNNC2 polyclonal Antibody

Product Synonym Names
TNNC2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
160
OMIM
191039
3D Structure
ModBase 3D Structure for P02585
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Troponin C, skeletal muscle protein (1-160aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-30481 / sc-8117 / sc-30480
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-TNNC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TNNC2 antibody
Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
Applications Tested/Suitable for anti-TNNC2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TNNC2 antibody
Recommended dilution: WB:1:500-2000
IHC:1:20-1:200

Western Blot (WB) of anti-TNNC2 antibody
All lanes: TNNC2 antibody at 10ug/ml+mouse skeletal muscleSecondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 18kDa
Observed band size: 18kDa

anti-TNNC2 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-TNNC2 antibody
Immunohistochemistry of paraffin-embedded human rectum using MBS1496004 at dilution 1:100
anti-TNNC2 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for TNNC2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
18,122 Da
NCBI Official Full Name
troponin C, skeletal muscle
NCBI Official Synonym Full Names
troponin C type 2 (fast)
NCBI Official Symbol
TNNC2  [Similar Products]
NCBI Protein Information
troponin C, skeletal muscle
UniProt Protein Name
Troponin C, skeletal muscle
Protein Family
UniProt Gene Name
TNNC2  [Similar Products]
UniProt Entry Name
TNNC2_HUMAN
NCBI Summary for TNNC2
Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008]
UniProt Comments for TNNC2
TNNC2: Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. Belongs to the troponin C family.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 20q12-q13.11

Cellular Component: cytosol; troponin complex

Molecular Function: actin binding; calcium ion binding; protein binding

Biological Process: muscle filament sliding; regulation of muscle contraction; skeletal muscle contraction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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