NP_612385.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,928 Da
NCBI Official Full Name
tetratricopeptide repeat protein 5
NCBI Official Synonym Full Names
tetratricopeptide repeat domain 5
NCBI Official Synonym Symbols
NCBI Protein Information
tetratricopeptide repeat protein 5
UniProt Protein Name
Tetratricopeptide repeat protein 5
UniProt Synonym Protein Names
Stress-responsive activator of p300; Strap
UniProt Synonym Gene Names
UniProt Entry Name
TTC5_HUMAN
UniProt Comments for TTC5
TTC5: Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 14q11.2
Cellular Component: cytoplasm; nucleoplasm
Molecular Function: chromatin binding; DNA binding; protein binding
Biological Process: DNA repair; positive regulation of transcription from RNA polymerase II promoter
Research Articles on TTC5
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Disclaimer
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Products associated with anti-TTC5 antibody
Pathways associated with anti-TTC5 antibody
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