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anti-ABCF1 antibody :: Rabbit ABCF1 Polyclonal Antibody

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Catalog # MBS9213384
Unit / Price
  0.08 mL  /  $155 +1 FREE 8GB USB
  0.4 mL  /  $340 +1 FREE 8GB USB
Product Name

ABCF1, Polyclonal Antibody

Also Known As

ABCF1 Antibody (C-term)

Product Synonym Names
ATP-binding cassette sub-family F member 1; ATP-binding cassette 50; TNF-alpha-stimulated ABC protein; ABCF1; ABC50
Antibody/Peptide Pairs
ABCF1 peptide (MBS9228118) is used for blocking the activity of ABCF1 antibody (MBS9213384)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
687-716
Immunogen Sequence Length
807
OMIM
603429
3D Structure
ModBase 3D Structure for Q8NE71
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human, mouse (Predicted Reactivity: Pig)
Specificity
This ABCF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 687-716 amino acids from the C-terminal region of human ABCF1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (lot specific)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ABCF1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABCF1 antibody
The protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process.
Product Categories/Family for anti-ABCF1 antibody
Applications Tested/Suitable for anti-ABCF1 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-ABCF1 antibody
WB~~1:1000

Western Blot (WB) of anti-ABCF1 antibody
Western blot analysis of ABCF1 Antibody (C-term) in NCI-H460 cell line lysates (35ug/lane). ABCF1 (arrow) was detected using the purified Pab.
anti-ABCF1 antibody Western Blot (WB) (WB) image
Western Blot (WB) of anti-ABCF1 antibody
Western blot analysis of ABCF1 Antibody (C-term) in mouse NIH-3T3 cell line lysates (35ug/lane). ABCF1 (arrow) was detected using the purified Pab.
anti-ABCF1 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ABCF1 antibody
ABCF1 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ABCF1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
anti-ABCF1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for ABCF1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
Human, mouse (Predicted Reactivity: Pig)NP_001081.1[Other Products]
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
95926
NCBI Official Full Name
ATP-binding cassette sub-family F member 1 isoform a
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family F (GCN20), member 1
NCBI Official Symbol
ABCF1  [Similar Products]
NCBI Official Synonym Symbols
ABC27; ABC50
  [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family F member 1
UniProt Protein Name
ATP-binding cassette sub-family F member 1
UniProt Synonym Protein Names
ATP-binding cassette 50; TNF-alpha-stimulated ABC protein
Protein Family
UniProt Gene Name
ABCF1  [Similar Products]
UniProt Synonym Gene Names
ABC50  [Similar Products]
UniProt Entry Name
ABCF1_HUMAN
NCBI Summary for ABCF1
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCF1
ABCF1: Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis. Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Translation

Chromosomal Location of Human Ortholog: 6p21.33

Cellular Component: nucleoplasm; polysomal ribosome; membrane; cytoplasm; ribosome; nuclear envelope

Molecular Function: protein binding; translation activator activity; translation factor activity, nucleic acid binding; ATPase activity; ribosome binding; ATP binding

Biological Process: translation; positive regulation of translation; translational initiation; ribosome biogenesis and assembly; inflammatory response
Product References and Citations for anti-ABCF1 antibody
Barcellos,L.F., et.al., PLoS Genet. 5 (10), E1000696 (2009) Paytubi,S., et.al., J. Biol. Chem. 284 (36), 24061-24073 (2009) Saito,A., et.al., J. Hum. Genet. 54 (6), 317-323 (2009)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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