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anti-5HT1B antibody :: Rabbit 5HT1B Polyclonal Antibody

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Catalog # MBS540154
Unit / Price
  0.1 mg Affinity-Purified  /  $390 +1 FREE 8GB USB
anti-5HT1B antibody
Product Name

5HT1B, Polyclonal Antibody

Also Known As

5HT1B Receptor Antibody Affinity Purified

Product Synonym Names
HTR1DB; S12; Serotonin 1D beta receptor antibody
Antibody/Peptide Pairs
5HT1B peptide (MBS542301) is used for blocking the activity of 5HT1B antibody (MBS540154)
Matching Pairs
Antibody: 5HT1B (MBS540154)
Positive Control: 5HT1B (MBS542495)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
386
3D Structure
ModBase 3D Structure for P28334
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Affinity Purified
Concentration
0.5-1.5 ug/ul in antibody stabilization buffer (lot specific)
Immunogen
Synthetic peptide taken within amino acid region 160-260 on rat 5HT1B
Molecular Function
Drug binding, serotonin receptor activity, serotonin binding
Structure
Homodimer. Heterodimer with HTR1D
Subcellular Location
Cell membrane; Multi-pass protein
Preparation and Storage
-20 degree C for long term storage
Other Notes
Small volumes of anti-5HT1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-5HT1B antibody
Affinity Purified 5 Hydroxytryptamine 1B receptor Antibody
G-protein coupled receptor for serotonin (5-hydroxytryptamine). Functions as a receptor for various drugs which cause conformational change upon ligand binding that triggers signaling via guanine nucleo-tide binding proteins and modulation of down-stream effectors like adenylate cyclase. Inhibits adenylate cyclase activity and activates phosphatidylinositol-calcium second messenger system that regulates release of intracellular Calcium ions.
Applications Tested/Suitable for anti-5HT1B antibody
ELISA (EIA), IMM, Western Blot (WB)
Application Notes for anti-5HT1B antibody
Dot Blot: 1:50,000
ELISA: 1:50,000
Immunoprecipitation: 1:200
Western Blot: 1:2,500-1:5,000
NCBI/Uniprot data below describe general gene information for 5HT1B. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
43,079 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 1B
NCBI Official Synonym Full Names
5-hydroxytryptamine (serotonin) receptor 1B
NCBI Official Symbol
Htr1b  [Similar Products]
NCBI Protein Information
5-hydroxytryptamine receptor 1B
UniProt Protein Name
5-hydroxytryptamine receptor 1B
UniProt Synonym Protein Names
Serotonin receptor 1B
UniProt Gene Name
Htr1b  [Similar Products]
UniProt Synonym Gene Names
5ht1b; 5-HT-1B; 5-HT1B  [Similar Products]
UniProt Entry Name
5HT1B_MOUSE
UniProt Comments for 5HT1B
5-HT(1B): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass

Cellular Component: cytoplasm; integral to membrane; integral to plasma membrane; membrane; plasma membrane

Molecular Function: drug binding; G-protein coupled receptor activity; serotonin binding; serotonin receptor activity; signal transducer activity

Biological Process: behavior; bone remodeling; drinking behavior; feeding behavior; G-protein coupled receptor internalization; G-protein coupled receptor protein signaling pathway; negative regulation of cAMP biosynthetic process; negative regulation of serotonin secretion; negative regulation of synaptic transmission, GABAergic; negative regulation of synaptic transmission, glutamatergic; protein kinase C activation; regulation of behavior; regulation of dopamine secretion; response to cocaine; response to drug; response to ethanol; response to toxin; serotonin receptor, adenylate cyclase inhibiting pathway; signal transduction; synaptic transmission; vasoconstriction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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