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anti-ADCY4 antibody :: Rabbit A Cyclase IV Polyclonal Antibody

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Catalog # MBS2537261
Unit / Price
  0.02 mL  /  $110 +1 FREE 8GB USB
  0.06 mL  /  $150 +1 FREE 8GB USB
  0.12 mL  /  $225 +1 FREE 8GB USB
  0.2 mL  /  $360 +1 FREE 8GB USB
Western Blot (WB)
Product Name

A Cyclase IV (ADCY4), Polyclonal Antibody

Full Product Name

A Cyclase IV Polyclonal Antibody

Product Synonym Names
ADCY4; Adenylate cyclase type 4; ATP pyrophosphate-lyase 4; Adenylate cyclase type IV; Adenylyl cyclase 4
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
600292
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Concentration
1 mg/ml (lot specific)
Immunogen
Synthesized peptide derived from the Internal region of human A Cyclase IV.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-ADCY4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ADCY4 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ADCY4 antibody
WB: 1:500-1:2000, ELISA: 1:5000-1:20000

Western Blot (WB) of anti-ADCY4 antibody
Western Blot analysis of Jurkat cells with A Cyclase IV Polyclonal Antibody.
anti-ADCY4 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for ADCY4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Calculated MW: 120
Observed MW: 120[Similar Products]
NCBI Official Full Name
adenylate cyclase type IV
NCBI Official Synonym Full Names
adenylate cyclase 4
NCBI Official Symbol
ADCY4  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
adenylate cyclase type 4
UniProt Protein Name
Adenylate cyclase type 4
UniProt Synonym Protein Names
ATP pyrophosphate-lyase 4; Adenylate cyclase type IV; Adenylyl cyclase 4
Protein Family
UniProt Gene Name
ADCY4  [Similar Products]
UniProt Entry Name
ADCY4_HUMAN
NCBI Summary for ADCY4
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
UniProt Comments for ADCY4
ADCY4: This is a membrane-bound, calmodulin-insensitive adenylyl cyclase. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Protein type: Transporter; Nucleotide Metabolism - purine; EC 4.6.1.1; Transporter, aquaporin family; Adenylyl cyclase; Membrane protein, multi-pass; Lyase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: cytoplasm; dendrite; integral to membrane; membrane; plasma membrane; protein complex

Molecular Function: adenylate cyclase activity; ATP binding; G-protein beta/gamma-subunit binding; metal ion binding; protein binding

Biological Process: activation of protein kinase A; cAMP biosynthetic process; cAMP-mediated signaling; energy reserve metabolic process; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; innate immune response; nerve growth factor receptor signaling pathway; phospholipase C activation; renal water homeostasis; signal transduction; synaptic transmission; transmembrane transport; water transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-ADCY4 antibody
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