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anti-AAK1 antibody :: Rabbit AAK1 Polyclonal Antibody

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Catalog # MBS840310
Unit / Price
  0.03 mg  /  $150 +1 FREE 8GB USB
  0.1 mg  /  $290 +1 FREE 8GB USB
Testing Data
Product Name

AAK1, Polyclonal Antibody

Also Known As

AAK1 Antibody

Product Synonym Names
AAK-1; AAK1; AKK 1; AP2 associated kinase 1; Adaptor associated kinase 1
Antibody/Peptide Pairs
AAK1 peptide (MBS843822) is used for blocking the activity of AAK1 antibody (MBS840310)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
657
OMIM
300819
3D Structure
ModBase 3D Structure for Q2M218
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity purified
Form/Format
100 ug (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Appearance: Colorless liquid
Concentration
0.5 mg/ml (lot specific)
Immunogen
Synthetic peptide surrounding amino acid 850 of human AAK1
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Other Notes
Small volumes of anti-AAK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AAK1 antibody
Background: AAK1 is a serine/threonine kinase that is thomught to coordinate the recruitment of AP-2 to receptors containing tyrosine-based internalization motifs by phosphorylating the u2 subunit. There is strong evidence that this protein is the endogenous mu 2 kinase and plays a regulatory role in clathrin-mediated endocytosis, including the regulation of fatty acid synthesis and cholesterol synthesis.
Applications Tested/Suitable for anti-AAK1 antibody
Western Blot (WB)
Application Notes for anti-AAK1 antibody
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~95 kDa AAK1 in samples from human, mouse and rat origins. Reactivity to other species has not been tested.

Testing Data of anti-AAK1 antibody
anti-AAK1 antibody Testing Data image
NCBI/Uniprot data below describe general gene information for AAK1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
74,515 Da
NCBI Official Full Name
zinc finger protein 630 isoform 1
NCBI Official Synonym Full Names
zinc finger protein 630
NCBI Official Symbol
ZNF630  [Similar Products]
NCBI Official Synonym Symbols
dJ54B20.2
  [Similar Products]
NCBI Protein Information
zinc finger protein 630
UniProt Protein Name
Zinc finger protein 630
UniProt Gene Name
ZNF630  [Similar Products]
UniProt Entry Name
ZN630_HUMAN
NCBI Summary for AAK1
This gene encodes a protein containing an N-terminal Kruppel-associated box-containing (KRAB) domain and 13 Kruppel-type C2H2 zinc finger domains. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
UniProt Comments for AAK1
ZNF630: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: Xp11.3-p11.1

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding; transcription factor activity

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-AAK1 antibody
Organs/Tissues associated with anti-AAK1 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with AAK1 and Brain
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